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Decapeptyl SR Injection 3mg – Triptorelin SR 3mg, 1 Injection
Decapeptyl SR 3mg is a powerful medication that has been designed to treat a variety of conditions in both men and women. The active ingredient in Decapeptyl SR 3mg—triptorelin—has been scientifically developed to closely resemble the gonadotropin releasing hormone found naturally in our bodies. For men, Decapeptyl SR 3mg works by lowering the levels of testosterone hormones. In women, it works by reducing oestrogen levels. With its highly advanced formula and proven effectiveness, Decapeptyl SR 3 mg is the perfect choice for anyone looking for an effective treatment.
In men, Decapeptyl SR 3 mg is used to treat prostate cancer.
In women, Decapeptyl SR 3 mg is used to treat:
• Endometriosis – a condition in which the tissue that normally lines the uterus (endometrium) grows in other places.
• Uterine fibroids – abnormal (benign) growth of cells in your uterus.
• Hormone responsive early stage breast cancer in pre-menopausal women who have received chemotherapy.
• Decapeptyl SR 3 mg is used together with hormone medicines. You will also be asked to take: A medicine called ‘tamoxifen’ – you will be asked to take this medicine if you are at high risk of the cancer coming back.
Or
An ‘aromatase inhibitor’ medicine such as ‘exemestane’ – you will have treatment with Decapeptyl SR 3 mg for at least 6 to 8 weeks before you start taking this medicine.
• Remember to read the patient leaflet for the medicine you take with Decapeptyl SR 3 mg
Decapeptyl SR Injection 3mg Reviews
After using Decapeptyl SR Injection 3mg, it’s helpful to let others know about your experience. Reviews of an item help other users know that medicines received have helped the condition it is claimed for, how well the treatment worked or any issues to be aware of. We invite our users to leave a review of both their treatment and of the service provided. Click on the reviews tab to see if there has been feedback on this item.
What is the price of Decapeptyl SR Injection 3mg?
The price of Decapeptyl SR Injection 3mg is £103.50
Where can you buy Decapeptyl SR Injection 3mg?
You can buy Decapeptyl SR Injection 3mg at Dock Pharmacy Essex UK, UK Online Pharmacy.
Can you buy Decapeptyl SR Injection 3mg Over the counter?
Decapeptyl SR Injection 3mg is not available to buy over the counter. You need a prescription to buy Decapeptyl SR Injection 3mg
| Brand |
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Brand
DECAPEPTYL
How To Use
How to use Decapeptyl SR 3 mg
MEN
Decapeptyl SR 3 mg will be injected into a muscle, usually your bottom, by a doctor or nurse. On this leaflet there are instructions for them that explain how to prepare the injection. You will normally receive an injection once every 28 days.
WOMEN
Decapeptyl SR 3 mg will be injected into a muscle, usually your bottom, by a doctor or nurse. On this leaflet there are instructions for them that explain how to prepare the injection. You will normally receive one injection every 28 days. This injection should be given in the first 5 days of your menstrual cycle. If you are being treated for uterine fibroids you should be treated for at least 3 months. You should not need to be treated for more than 6 months.
Product Details
What you need to know before you use Decapeptyl SR 3 mg
MEN Do not use Decapeptyl SR 3 mg • If you are allergic to triptorelin or similar types of drugs (other GnRH agonists) or any of the other ingredients of this medicine (listed in section 6). Warnings and precautions Talk to your doctor or pharmacist before taking Decapeptyl SR 3 mg. • There have been reports of depression in patients taking Decapeptyl SR 3 mg which may be severe. If you are taking Decapeptyl SR 3 mg and develop depressed mood, inform your doctor. Your doctor may want to monitor your depression during treatment. • If you are using medicines for preventing your blood clotting, you may experience bruising at the site of the intramuscular injection. • In adults, triptorelin may cause thinning of the bones (osteoporosis) with an increased risk of bone fractures. You should therefore tell your doctor if you have any of the below risk factors as he/she might give you bisphosphonate (drugs used to treat wark bones) to treat bone loss. Risk factors may include: o If you or any of your close family have thinning of the bones. o If you drink excessive amounts of alcohol, and/or smoke heavily. o If you take medicines over a long period of time that may cause thinning of the bones, for example medicines for epilepsy or steroids (such as hydrocortisone or prednisolone). • When you first start treatment with Decapeptyl SR 3 mg it actually increases the level of your hormones for a short time. This means that you may feel worse to begin with (see section 4 ‘Possible side effects’ for more information). The doctor may give you some medicine (an anti-androgen) to prevent your symptoms from getting worse. After a short time, the amount of hormone will drop and your symptoms will get better. • If you suffer from urinary obstruction or spinal cord (nerves in your backbone) compression due to your prostate cancer spreading, your doctor will supervise you closely for the first few weeks of treatment. If you experience difficulty passing urine, bone pain, weakness of lower limbs or pins and needles sensation, contact your doctor immediately, who will assess and treat you appropriately. • Tell your doctor if you have diabetes. • Tell your doctor if you have any heart or blood vessel conditions, including heart rhythm problems (arrhythmia), or are being treated with medicines for these conditions. The risk of heart rhythm problems may be increased when using Decapeptyl SR 3 mg. • If you have an enlargement (benign tumour) of the pituitary gland that you were unaware of, this may be discovered during treatment with Decapeptyl SR 3 mg. Symptoms include sudden headache, problems with eyesight and paralysis of the eye muscles. • After surgical castration triptorelin does not induce any further decrease in serum testosterone levels. • Diagnostic tests of pituitary gonadal function or sex organs conducted during treatment or after discontinuation of therapy with Decapeptyl SR 3 mg may be misleading. • Testosterone decreasing agents may cause changes in ECG associated with heart rhythm abnormalities (QT prolongation). • Tell your doctor if you have back pain, weakness, numbness or tingling in your legs. Page 3 of 11 Your doctor may give you another drug to help you feel better during this time. Other medicines and Decapeptyl SR 3 mg Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines. Decapeptyl SR 3 mg might interfere with some medicines used to treat heart rhythm problems (e.g. quinidine, procainamide, amiodarone and sotalol) or might increase the risk of heart rhythm problems when used with some other drugs (e.g. methadone (used for pain relief and part of drug addiction detoxification), moxifloxacin (an antibiotic), antipsychotics used for serious mental illnesses). Drugs which increase the level of a hormone called prolactin may react with Decapeptyl SR 3 mg. Many different kinds of drugs may increase prolactin levels. Driving and using machines You may feel dizzy, tired or have problems with your sight such as blurred vision. These are possible side effects of treatment or from the underlying disease. If you experience any of these side effects, you should not drive or use machines. Decapeptyl SR 3 mg contains sodium This medicine contains less than 1 mmol (23 mg) sodium per dose, i.e., essentially ‘sodium-free‘. WOMEN Do not use Decapeptyl SR 3 mg • If you are allergic to triptorelin or similar types of drugs (other GnRH agonists) or any of the other ingredients of this medicine (listed in section 6). • If you are pregnant or breast-feeding. • If you are using Decapeptyl SR 3 mg for breast cancer, do not use an ‘aromatase inhibitor’ medicine (such as exemestane) with Decapeptyl SR 3 mg until you have been treated with Decapeptyl SR 3 mg for at least 6 to 8 weeks. Warnings and precautions Talk to your doctor or pharmacist before taking Decapeptyl SR 3 mg. • Due to lack of clinical experience in women under 18 years of age, triptorelin is not recommended in adolescent and young women as it might cause thinning of bone. • There have been reports of depression in patients taking Decapeptyl SR 3 mg which may be severe. If you are taking Decapeptyl SR 3 mg and develop depressed mood, inform your doctor. Your doctor may want to monitor your depression during treatment. • If you are using medicines for preventing your blood clotting, you may experience bruising at the site of the intramuscular injection. • In adults, triptorelin may cause thinning of the bones (osteoporosis) with an increased risk of bone fractures. You should therefore tell your doctor if you have any of the below risk factors as he/she might give you bisphosphonate (drugs used to treat wark bones) to treat bone loss. Risk factors may include: o If you or any of your close family have thinning of the bones. o If you drink excessive amounts of alcohol, and/or smoke heavily. o If you take medicines over a long period of time that may cause thinning of the bones, for example medicines for epilepsy or steroids (such as hydrocortisone or prednisolone). • You may have some vaginal bleeding in the first month of treatment. After that your periods normally stop. • Tell your doctor if you have bleeding after the first month of treatment. • Your periods should start approximately 2 months after the last injection. Page 4 of 11 • You must use some form of contraception other than the ‘pill’ while you are having treatment and until you start your next period. Your doctor may suggest using a barrier method of contraception such as a condom or diaphragm (cap). • If you are a woman with submucous fibroids (benign tumours in the muscle underneath the lining of the womb), Triptorelin can cause bleeding when the fibroids break-down within the first 6-10 weeks after starting treatment. Contact your doctor immediately if you experience severe or unusual bleeding or pain. • If you have an enlargement (benign tumour) of the pituitary gland that you were unaware of, this may be discovered during treatment. Symptoms include sudden headache, problems with eyesight and paralysis of the eye muscles. If you are using Decapeptyl SR 3mg for Breast cancer: If you have anything wrong with you that affects your bones, such as osteoporosis, inform your doctor. This may affect the way you doctor decides to treat you. Your doctor will do a bone scan before treatment starts if you are at risk of osteoporosis and monitor you during treatment. If you have diabetes or high blood pressure, inform your doctor. Your doctor will check your blood sugar levels and blood pressure during treatment. Tell your doctor if you suffer from heart problems. If you suffer from depression, inform your doctor. Your doctor may want to monitor your depression during treatment. If you discontinue triptorelin treatment, you must discontinue at the same time aromatase inhibitor (such as exemestane) treatment. Other medicines and Decapeptyl SR 3 mg Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines. Drugs which increase the level of a hormone called prolactin may react with Decapeptyl SR 3 mg. Many different kinds of drugs may increase prolactin levels. Pregnancy and breast-feeding Do not take Decapeptyl SR 3 mg if you are pregnant or breast-feeding. Driving and using machines You may feel dizzy, tired or have problems with your sight such as blurred vision. These are possible side effects of treatment or from the underlying disease. If you experience any of these side effects, you should not drive or use machines. Decapeptyl SR 3 mg contains sodium This medicine contains less than 1 mmol (23 mg) sodium per dose, i.e., essentially ‘sodium-free‘
Side Effects
Possible side effects
Like all medicines, Decapeptyl SR 3 mg can have side effects although not everybody gets them. In rare cases you may experience a severe allergic reaction (angioedema, anaphylactic reaction). Tell your doctor immediately if you develop symptoms such as swallowing or breathing problems, dizziness, a rash, swelling of your lips, face, throat or tongue. MEN Many of the side effects are expected, due to the change in the level of testosterone in your body. These effects include hot flushes, impotence and decreased libido. Side effects which are very common (may affect more than 1 in 10 people) are hot flushes, weakness, excessive sweating, back pain, pins and needles sensation in the legs, reduced libido and impotence. Side effects which are common (may affect up to 1 in 10 people) are nausea, dry mouth, pain, bruising, redness and swelling at injection site, muscle and bone pain, pain in the arms and legs, oedema (build-up of fluid in the body tissues), lower abdominal pain, high blood pressure, allergic reaction, increase in weight, dizziness, headache, loss of libido, depression and mood changes. Side effects which are uncommon (may affect up to 1 in 100 people) are increase of blood platelets, feeling your heartbeat, ringing in the ears, vertigo, blurred vision, pain in abdomen, constipation, diarrhoea, vomiting, drowsiness, severe shivering associated with sweating and a fever, sleepiness, pain, swelling of the ankles, feet or fingers, some blood tests affected (including raised liver function tests), blood pressure increased, weight loss, loss of appetite, increase of appetite, gout (severe pain and swelling in the joints usually in the big toe), diabetes, excessive lipids in the blood, joint pain, muscle cramp, muscle weakness, muscle pain, bone pain, tingling or numbness, inability to sleep, feeling of irritability, development of enlarged breasts in men, breast pain, reduction in testicular size, pain in testicles, difficulty in breathing, acne, hair loss, itching, rash, redness of skin, hives, waking up to pass urine, problems passing urine and nosebleeds. Side effects which are rare (may affect up to 1 in 1,000 people) are red or purple discolorations on the skin, abnormal sensation in the eye, blurring or disturbance in vision, sensation of fullness in the abdomen, flatulence, Page 7 of 11 abnormal sense of taste, chest pain, difficulty in standing, flu-like symptoms, fever, anaphylactic reaction (serious allergic reaction which can cause dizziness or difficulty in breathing, swelling of the face or the throat), inflammation of the nose/throat, increased body temperature, stiff joints, joint swelling, musculoskeletal stiffness, osteoarthritis, memory loss, feeling confused, decreased activity, having a feeling of elation, shortness of breath when lying flat, blisters and low blood pressure. During post-marketing surveillance the following side effects have also been reported (their frequency cannot be estimated from the available data): changes in ECG (QT prolongation), serious allergic reaction which can lead to a swelling of the face, the tongue and the neck, dizziness or breathing difficulties (Quincke oedema, anaphylactic shock), general discomfort, anxiety, rapid formation of wheals due to swelling of the skin or mucous membranes and urinary incontinence, if there is an existing pituitary tumour there is an increased risk of bleeding to the area. An increase in white blood cell count may be found, as with other GnRH analogues, in patients being treated with Decapeptyl SR 3 mg. Patients receiving long-term treatment by GnRH analogue in combination with radiation may have more side effects especially gastrointestinal, related to radiotherapy. WOMEN Many of the side effects are expected due to the change in the level of oestrogens in your body. These very common side effects (may affect more than 1 in 10 people) include headache, decreased libido, mood swings, difficulty in sleeping, breast disorder, ovarian hyperstimulation syndrome, pain during or after sexual intercourse, painful periods, genital bleeding, pelvic pain, dryness of the vagina, weakness, excessive sweating, acne, oily skin and hot flushes. Side effects which are common (may affect up to 1 in 10 people) are breast pain, muscle cramps, painful joints, weight gain, feeling sick, depression (long term treatment), nervousness, abdominal pain or discomfort, pain, bruising, redness and swelling at injection site, swelling of ankles, feet or fingers, allergic reaction, pain in the arms and legs, dizziness. Side effects which are uncommon (may affect up to 1 in 100 people) are feeling your hearbeat, vertigo, dry eye, blurred vision, bloating, vomiting, diarrhoea, dry mouth, flatulence, mouth ulcer, weight decrease, decrease in appetite, water retention, back pain, muscle pain, abnormal taste, loss of sensations, temporary loss of consciousness, memory loss, lack of concentration, tingling or numbness, involuntary muscle movement, mood change, anxiety, disorientation, depression (short term treatment), bleeding after sex, prolapse, irregular period, painful period and heavy period, small cysts (swelling) on the ovaries which can cause pain, discharge from the vagina, difficulty breathing, nosebleed, hair loss, dry skin, excessive bodily hair, brittle nails, itching, and skin rash. During post-marketing surveillance the following side effects have also been reported (their frequency cannot be estimated from the available data): general discomfort, increased blood pressure, increased body temperature, serious allergic reaction which can lead to a swelling of the face, the tongue and the neck, dizziness or breathing difficulties (Quincke oedema, anaphylactic shock), some blood tests affected (including raised liver function tests) muscle weakness, confusion, absence of menstrual periods, rapid formation of wheals due to swelling of the skin or mucous membranes, abnormal sensations in the eyes and/or changes in sight, hives, if there is an existing pituitary tumour there is an increased risk of bleeding to the area. Page 8 of 11 In endometriosis treatment, the disorders for which the treatment has been justified (pelvic pain, dysmenorrhea) may be exacerbated at the beginning of the treatment, but should disappear in one to two weeks. This may occur even if the treatment is producing a favorable effect. You should nevertheless immediately notify your doctor of this phenomenon. Side effects when used for breast cancer in combination with either tamoxifen or an aromatase inhibitor The following side effects have been seen when Decapeptyl SR 3 mg has been used for breast cancer in combination with either tamoxifen or an aromatase inhibitor: Very common effects (affect more than 1 patient in 10): nausea, feeling very tired, joint and muscle pain, osteoporosis, hot flushes, excessive sweating, difficulty in sleeping, depression, decreased libido, dryness of the vagina, pain during or after sexual intercourse, urinary incontinence, increased blood pressure. Common side effects (affect 1 to 10 patients of 100): diabetes, high blood sugar (hyperglycaemia), pain, bruising, redness and swelling at injection site, allergic reaction, bone fractures, blood clot in a blood vessel. Uncommon side effects (affect 1 to 10 patients of 1000): bleed in the brain, lack of blood supply to the brain or the heart. Rare side effects (affect 1 to 10 patients of 10,000): change in ECG (QT prolongation). Reporting of side effects If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme. Website: www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store. By reporting side effects, you can help provide more information on the safety of this medicine.
Ingredients
What Decapeptyl SR 3 mg contains:
The active substance of Decapeptyl SR 3 mg is triptorelin.
Each vial contains sufficient quantity of triptorelin (as triptorelin acetate) to ensure that the minimum triptorelin quantity injected is 3 mg.
The other ingredients are D,L lactide-glycolide copolymer, mannitol, carmellose sodium, polysorbate 80
How to Store
How to store Decapeptyl SR 3 mg
Keep this medicine out of the sight and reach of children. Do not use the vial or ampoule after the expiry date printed on the box. This medicine should not be stored above 25°C. The vial and ampoule should be kept in the outer box. Do not throw away any medicines via wastewater or household waste. Ask your pharmacist how to throw away medicines you no longer use. These measures will help protect the environment.
Patient Information leaflet
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