Product Details

What you need to know before you take Periostat

Do not take Periostat: – if you are allergic to doxycycline (or any other tetracycline antibiotic e.g. oxytetracycline, tetracycline, chlortetracycline, demeclocycline or minocycline) or any of the ingredients of this medicine (listed in section 6). – if you are pregnant or think you might be pregnant – if you are planning to become pregnant – if you are breast-feeding – if you have achlorhydria (lack of acid in the stomach) plaque Destructive enzymes (collagenase) Tissue damage results from too much collagenase Remove bacteria with scaling and root planing The activity of the destructive enzymes is then reduced by Periostat Periostat Tabs PIL UK 010 If any of the above applies to you, or if you are not sure, speak to your dentist, doctor or pharmacist before you take Periostat. Warnings and precautions Talk to your dentist, doctor or pharmacist before taking Periostat if: – you have porphyria (a disease which causes stomach pain, constipation, changes in the colour of urine, skin rashes and disturbed behaviour) – you have severe diarrhoea (see Section 4 Possible side effects) – you have myasthenia gravis (a rare muscle weakness disorder) – you suffer from phototoxicity (skin rashes caused by sunlight). Stop taking Periostat if this happens and consult your doctor. – you have liver problems or are taking medication which may damage your liver (see Section 4 Possible side effects) – you have thrush (a yeast infection caused by Candida) – you have systemic lupus erythematosus (SLE). An allergic condition which causes joint pain, skin rashes and fever (see Section 4 Possible side effects) Children and adolescents Do not give this medicine to children up to 12 years of age. Other medicines and Periostat Tell your dentist, doctor or pharmacist if you are taking, have recently taken or might take any other medicines. • aluminium containing products • zinc containing products • calcium containing products (used to neutralise acid in your stomach) (used to treat low zinc levels) (used to treat low calcium levels or as an antacid) • anti-coagulant medication for example warfarin (used to thin the blood) • penicillin or rifampicin (antibiotics to treat infections) • antacids (used to neutralise acid in your stomach) • iron containing products • bismuth containing products • sucralfate-containing products (used to treat low iron levels) (used to treat stomach ulcers) (used to treat stomach ulcers) • activated charcoal (used to treat poisoning) • cholestyramine (used to reduce cholesterol levels and prevent heart disease, to treat itching due to liver problems and diarrhoea) • didanosine tablets (used to treat HIV) • quinapril (used to treat high blood pressure or heart failure) • barbiturates, carbamazepine, phenytoin and primidone (medication to control epilepsy) • ciclosporins (used to suppress your immune system after an organ transplant) • methoxyflurane (a type of anaesthetic) • isotretinoin (used to treat acne) • sulfonylurea agents (used to treat diabetes, e.g. chlorpropamide, glibenclamide, gliclazide, glimepiride, glipizide or gliquidone) • oral contraceptives (used to prevent pregnancy). Periostat Tabs PIL UK 010 Periostat with food, drink and alcohol Periostat should be taken at least one hour before meals. Food containing large amounts of calcium (e.g. milk, dairy products and calcium-containing fruit juices) should be avoided until at least 2 to 3 hours after taking Periostat. Consult with your doctor before taking Periostat if you regularly drink large amounts of alcohol. Pregnancy, breast-feeding and fertility If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your dentist, doctor or pharmacist for advice before taking this medicine. Periostat should not be used during pregnancy or if you are breast-feeding. Taking Periostat during pregnancy may result in permanent discolouration of your child’s teeth. Periostat passes into the milk of breast-feeding mothers and therefore you should not breastfeed whilst taking this medicine. There are no clinical data regarding the potential effect of Periostat on fertility. Driving and using machines Taking Periostat may make you feel sick or dizzy. If you are affected, you should not drive or use machines until the effect has worn off. Periostat contains lactose If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicine.