Product Details

Product Information of Synarel Nasal Spray

What you need to know before you take Synarel

Ì Do not use Synarel • If you are allergic to nafarelin acetate, gonadotrophin releasing hormone or any of the other ingredients of this medicine (listed in section 6). • If you are pregnant or may become pregnant whilst taking Synarel. If you are taking Synarel as part of a fertility programme, your pregnancy will be planned to take place after you stop taking this medicine. • If you suffer from vaginal bleeding, for which your doctor could not find the cause. • If you are currently breast-feeding. • If you are under 18 years of age. Ì Warnings and precautions Talk to your doctor or pharmacist before using Synarel • If you suffer from Polycystic Ovarian Disease as there is a potential risk for excessive follicular stimulation • If you think you might be pregnant there is a risk to the development of the foetus and/or miscarriage. • There have been reports of depression in patients taking Synarel which may be severe. If you are taking Synarel and develop depressed mood, inform your doctor. • Use of Synarel in combination with gonadotropin to treat infertility can sometimes cause an overreaction in your ovaries (ovarian hyperstimulation syndrome, OHSS). You may notice stomach pain, swelling of your stomach, and feeling or being sick. If this happens, tell your doctor. See also section 4 Possible side effects. Your doctor will advise whether you can still take Synarel. • After a course of therapy, if further treatment of endometriosis and fibroids with Synarel is needed your bone density may need to be checked. • Tell your doctor if you are due to have any medical tests as use of this medicine might alter/ affect the results. Ì Other medicines and Synarel Tell your doctor or pharmacist if you are using, have recently used, or might use any other medicines. Nasal decongestants should not be used within the 30 minute period before taking a dose of Synarel as they can significantly reduce absorption of the medicine in the nose. If your nose is congested, Synarel will still be absorbed. If you have been using an oral contraceptive to prevent pregnancy, your doctor will ask you to stop taking these and use a barrier method of contraception (diaphragm, condom) to stop you becoming pregnant. Ì Synarel with food and drink Please refer to section 3. Ì Pregnancy, breast-feeding and fertility Do not take Synarel if you are pregnant or trying to become pregnant. Do not take Synarel if you are breast-feeding. Ì Driving and using machines Page 3 of 9 Synarel is not known to affect the ability to drive or use machinery. Ì Synarel contains benzalkonium chloride Benzalkonium chloride (a type of preservative) is an irritant and may cause skin reactions, swelling and bronchospasm. 3. How to use Synarel Always use this medicine exactly as your doctor or pharmacist has told you. Check with your doctor or pharmacist if you are not sure. Synarel can be taken with or without food. • Synarel can only be taken/administered through the nose by nasal spray. • If you sneeze while spraying Synarel, you will need to take another dose of Synarel.