Product Details

What you need to know before you take Disulfiram tablets

Do not take Disulfiram tablets if you have: • an allergy (hypersensitivity) to disulfiram or any of the other ingredients of this medicine (listed in section 6) • severe heart disease or heart failure • high blood pressure • severe psychiatric or personality disorder • had a stroke. • recently consumed alcohol Warnings and precautions Talk to your doctor or pharmacist before taking Disulfiramtablets if you have: • kidney, liver or lung disease • diabetes • low blood pressure • brain damage • epilepsy. Children and adolescents Do not give this medicine to children. Other medicines and Disulfiram Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines, including medicines obtained without a prescription. Especially: • warfarin (reduces blood clotting) • phenytoin and paraldehyde (to treat epilepsy) • theophylline (to treat asthma) • chlordiazepoxide and diazepam (to treat anxiety)

pethidine and morphine (painkillers) • amphetamines (stimulants) • pimozide, and chlorpromazine (to treat mental illnesses) • isoniazid metronidazole, rifampicin (to treat infections) • amitriptyline (to treat depression) Other precautions Certain foods, liquid medicines, remedies, tonics, toiletries, perfumes and sprays may contain enough alcohol to cause a Disulfiram tablet -alcohol reaction. Caution should also be exercised with low alcohol and “non-alcoholic” or “alcohol-free” beers and wines. If enough is taken they may produce unpleasant reactions. Pregnancy and breast-feeding If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine. The use of Disulfiramtablet during the first 3 months of pregnancy or breast-feeding is not advised and should only be used if directed by your doctor. Driving and using machines Disulfiram tablets may cause drowsiness or tiredness (see ‘4. Possible side effects’). If you are affected do not drive or operate machinery. Disulfiram and lactose If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicinal product. Disulfiram and sodium. This medicine contains less than 1 mmol sodium (23 mg) per tablet, that is to say essentially ‘sodiumfree’. Disulfiram and Alcohol If you drink alcohol during or within 2 weeks of stopping Disulfiram tablets, or you have been exposed to alcohol from other sources (see ‘Other precautions’) a Disulfiram-alcohol reaction may occur. The reaction is unpredictable and symptoms may be severe or life threatening. Symptoms include; flushing of the face and neck, increased body temperature, sweating, feeling or being sick, itchy skin or rash caused by an allergic reaction (pruritis, urticaria) anxiety, dizziness, headache, blurred vision, difficulty breathing, palpitations, rapid breathing. In severe cases; rapid heart beat, low blood pressure, abnormally slow breathing, chest pain, abnormal heart rhythm, coma or fits may occur. Rare complications may include; high blood pressure, breathing problems, blood disorders. If you get some of the symptoms, contact your doctor. The Disulfiram-alcohol reaction can occur within 15 minutes after drinking alcohol and may last several hours.