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What you need to know before you use ESTRING
Medical check-up
ESTRING may not be suitable for all women. Before you start using ESTRING, your doctor
should ask about your own and your family’s medical history. Your doctor may decide to
examine your breasts and/or your abdomen, and may do an internal examination – but only if
these examinations are necessary for you, or if you have any special concerns.
Once you’ve started on HRT, it is recommended that you see your doctor for regular checkups (at least once a year). At these check-ups, your doctor may discuss with you the benefits
and risks of continuing to take HRT.
Be sure to:
• go for regular breast screening and cervical smear tests
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• regularly check your breasts for any changes such as dimpling of the skin, changes
in the nipple, or any lumps you can see or feel
Do not use ESTRING if you have the following conditions:
• you are allergic to estradiol or similar medicines for hormone replacement therapy, or
any of the other ingredients of this medicine (listed in section 6)
• hereditary blood disorder (porphyria)
• cancer that is sensitive to oestrogen e.g. endometrial cancer (cancer of the womb) or
if you are suspected of having it
• previous or current history of an ‘embolus’ (blood clots that travel through the
bloodstream and block blood vessels in the leg or elsewhere, also called ‘deep vein
thrombosis’ (DVT))
• you have or have ever had breast cancer, or if you are suspected of having it
• vaginal bleeding which you have not made your doctor aware of
• previous or current liver disease where liver function tests are still abnormal
• overgrown lining of your womb (untreated endometrial hyperplasia)
• previous or a present case of blocked arteries that could cause cardiovascular diseases
like angina or a heart attack
• blood clotting disorder (thrombophilic disorder such as protein C, protein S or antithrombin deficiency).