Istin 5mg Tablets, containing Amlodipine 5mg, are a trusted treatment for managing high blood pressure (hypertension) and relieving chest pain (angina). As a calcium channel blocker, Amlodipine works by relaxing blood vessels, improving blood flow, and reducing strain on the heart. In addition to human use, Amlodipine is also prescribed in veterinary medicine to manage hypertension and cardiovascular conditions in cats and dogs.
Q: How does Amlodipine work?
A: Amlodipine relaxes blood vessels, improving blood flow and reducing the heart’s workload, making it effective for both hypertension and angina.
Q: Can Istin 5mg Tablets be used for pets?
A: Yes, Amlodipine is commonly prescribed by veterinarians to manage hypertension in cats and dogs.
Q: Are there any dietary restrictions while taking Istin?
A: No specific restrictions, but maintaining a healthy, low-sodium diet is beneficial for managing hypertension.
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The price of Istin 5mg Tablets is £16.62
You can buy Istin 5mg Tablets at Dock Pharmacy Essex UK, UK Online Pharmacy.
Istin 5mg Tablets is not available to buy over the counter. You need a prescription to buy Istin 5mg Tablets
Take control of your cardiovascular health with Istin 5mg Tablets (Amlodipine 5mg). Trusted for human and veterinary use, this versatile medication offers effective hypertension and angina management. Order now Istin or the generic version of Amlodipine from Dock Pharmacy for reliable and fast delivery.
Note: Always use Istin Tablets under the supervision of a qualified healthcare provider or veterinarian. Adhere to the prescribed dosage and seek medical advice if side effects occur.
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Always take this medicine exactly as your doctor or pharmacist has told you.
Check with your doctor or pharmacist if you are not sure.
The recommended initial dose is Istin 5 mg once daily.
The dose can be increased to Istin 10 mg once daily.
This medicine can be used before or after food and drinks.
You should take this medicine at the same time each day with a drink of water.
Do not take Istin with grapefruit juice. Use in children and adolescents For children and adolescents (6-17 years old), the recommended usual starting dose is 2.5 mg a day. The maximum recommended dose is 5 mg a day. Istin 5 mg tablets can be divided into halves to provide a 2.5 mg dose. It is important to keep taking the tablets. Do not wait until your tablets are finished before seeing your doctor. If you take more Istin than you should Taking too many tablets may cause your blood pressure to become low or even dangerously low. You may feel dizzy, lightheaded, faint or weak. If blood pressure drop is severe enough shock can occur. Your skin could feel cool and clammy and you could lose consciousness. Seek immediate medical attention if you take too many Istin tablets. If you forget to take Istin Do not worry. If you forget to take a tablet, leave out that dose completely. Take your next dose at the right time. Do not take a double dose to make up for a forgotten dose. If you stop taking Istin Your doctor will advise you how long to take this medicine. Your condition may return if you stop using this medicine before you are advised. If you have any further questions on the use of this medicine, ask your doctor or pharmacist
What you need to know before you take Istin
Do not take Istin • If you are allergic (hypersensitive) to amlodipine, or any of the other ingredients of this medicine listed in section 6, or to any other calcium antagonists. This may be itching, reddening of the skin or difficulty in breathing. • If you have severe low blood pressure (hypotension). •If you have narrowing of the aortic heart valve (aortic stenosis) or cardiogenic shock (a condition where your heart is unable to supply enough blood to the body). •If you suffer from heart failure after a heart attack. Warnings and precautions Talk to your doctor or pharmacist before taking Istin. You should inform your doctor if you have or have had any of the following conditions: Page 2 of 7 • Recent heart attack • Heart failure • Severe increase in blood pressure (Hypertensive crisis) • Liver disease • You are elderly and your dose needs to be increased Children and adolescents Istin has not been studied in children under the age of 6 years. Istin should only be used for hypertension in children and adolescents from 6 years to 17 years of age (see section 3). For more information, talk to your doctor. Other medicines and Istin Tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription. Istin may affect or be affected by other medicines, such as: • ketoconazole, itraconazole (anti-fungal medicines) • ritonavir, indinavir, nelfinavir (so called protease inhibitors used to treat HIV) • rifampicin, erythromycin, clarithromycin (antibiotics) • hypericum perforatum (St. John’s Wort) • verapamil, diltiazem (heart medicines) • dantrolene (infusion for severe body temperature abnormalities) • tacrolimus, sirolimus, temsirolimus, and everolimus (medicines used to alter the way your immune system works) • simvastatin (cholesterol lowering medicine) • cyclosporine (an immunosuppressant) Istin may lower your blood pressure even more if you are already taking other medicines to treat your high blood pressure. Istin with food and drink Grapefruit juice and grapefruit should not be consumed by people who are taking Istin. This is because grapefruit and grapefruit juice can lead to an increase in the blood levels of the active ingredient amlodipine, which can cause an unpredictable increase in the blood pressure lowering effect of Istin. Pregnancy and breast-feeding Pregnancy The safety of amlodipine in human pregnancy has not been established. If you think you might be pregnant, or are planning to get pregnant, you must tell your doctor before you take Istin. Breast-feeding Amlodipine has been shown to pass into breast milk in small amounts. If you are breast-feeding or about to start breast-feeding you must tell your doctor before taking Istin. Page 3 of 7 Ask your doctor or pharmacist for advice before taking any medicine. Driving and using machines Istin may affect your ability to drive or use machines. If the tablets make you feel sick, dizzy or tired, or give you a headache, do not drive or use machines and contact your doctor immediately. Istin contains sodium This medicine contains less than 1 mmol sodium (23 mg) per tablet, that is to say essentially ‘sodium-free’.
Possible side effects
Like all medicines, this medicine can cause side effects, although not everybody gets them. Visit your doctor immediately if you experience any of the following side effects after taking this medicine. • Sudden wheeziness, chest pain, shortness of breath or difficulty in breathing • Swelling of eyelids, face or lips • Swelling of the tongue and throat which causes great difficulty breathing • Severe skin reactions including intense skin rash, hives, reddening of the skin over your whole body, severe itching, blistering, peeling and swelling of the skin, inflammation of mucous membranes (Stevens Johnson Syndrome, toxic epidermal necrolysis) or other allergic reactions • Heart attack, abnormal heart beat • Inflamed pancreas which may cause severe abdominal and back pain accompanied with feeling very unwell The following very common side effect has been reported. If this causes you problems or if it lastsfor more than one week, you should contact your doctor. Very common: may affect more than 1 in 10 people • Oedema (fluid retention) The following common side effects have been reported. If any of these cause you problems or if they last for more than one week, you should contact your doctor. Common: may affect up to 1 in 10 people • Headache, dizziness, sleepiness (especially at the beginning of treatment) • Palpitations(awareness of your heart beat), flushing • Abdominal pain, feeling sick (nausea) • Altered bowel habits, diarrhoea, constipation, indigestion • Tiredness, weakness • Visual disturbances, double vision • Muscle cramps • Ankle swelling Other side effects that have been reported include the following list. If any of these get serious, or if you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist. Uncommon: may affect up to 1 in 100 people • Mood changes, anxiety, depression, sleeplessness • Trembling, taste abnormalities, fainting • Numbness or tingling sensation in your limbs, loss of pain sensation • Ringing in the ears • Low blood pressure • Sneezing/running nose caused by inflammation of the lining of the nose (rhinitis) • Cough • Dry mouth, vomiting (being sick) Page 5 of 7 • Hair loss, increased sweating, itchy skin, red patches on skin, skin discolouration • Disorder in passing urine, increased need to urinate at night, increased number of times of passing urine • Inability to obtain an erection, discomfort or enlargement of the breasts in men • Pain, feeling unwell • Joint or muscle pain, back pain • Weight increase or decrease Rare: may affect up to 1 in 1,000 people • Confusion Very rare: may affect up to 1 in 10,000 people • Decreased numbers of white blood cells, decrease in blood platelets which may result in unusual bruising or easy bleeding • Excess sugar in blood (hyperglycaemia) • A disorder of the nerves which can cause muscular weakness, tingling or numbness • Swelling of the gums • Abdominal bloating (gastritis) • Abnormal liver function, inflammation of the liver (hepatitis), yellowing of the skin (jaundice), liver enzyme increase which may have an effect on some medical tests • Increased muscle tension • Inflammation of blood vessels, often with skin rash • Sensitivity to light • Disorders combining rigidity, tremor, and/or movement disorders Not known: frequency cannot be estimated from the available data • Trembling, rigid posture, mask-like face, slow movements and a shuffling, unbalanced walk Reporting of side effects If you get any side effects, talk to your doctor or pharmacist or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly (see details below). By reporting side effects you can help provide more information on the safety of this medicine. United Kingdom Yellow Card Scheme website: www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store.
The active substance in Istin 10 mg tablets is amlodipine (as besilate).
The other ingredients are calcium hydrogen phosphate anhydrous, magnesium stearate, microcrystalline cellulose and sodium starch glycolate Type A.
Keep this medicine out of the sight and reach of children. Do not use this medicine after the expiry date which is stated on the pack after ‘EXP’. The expiry date refers to the last day of that month. Tablets Do not store above 25°C. Do not throw away any medicines via wastewater or household waste. Ask your pharmacist how to throw away medicines you no longer use. These measures will help protect the environment.
Click here for the Patient Information leaflet of Istin 5mg Tablets
Please read before using the product
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