Do not use Kentera:

• If you are hypersensitive (allergic) to oxybutynin or any of the ingredients of Kentera.
• If you have a rare condition called myasthenia gravis that makes the muscles in the body become weak and tire easily.
• If you experience incomplete bladder emptying during urination, the use of oxybutynin may increase this problem. You should discuss this problem with your doctor before using Kentera.
• If you have digestion problems caused by reduced emptying of the stomach after a meal you should consult your doctor before using Kentera.
• If you have glaucoma or a family history of glaucoma, tell your doctor.

Take special care with Kentera:

If you have any of the following:

• Liver problems
• Kidney problems
• Difficulty urinating
• Intestinal blockage
• Bloody stools
• Generalized muscle weakness
• Painful swallowing

Since treatment with oxybutynin may cause decreased perspiration, there is an increased risk of fever and heat stroke if you are exposed to high environmental temperatures.

Kentera is not recommended for use in children or adolescents.

Taking other medicines

Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.

Applying the Kentera patch at the same time as taking other medicines that have similar side effects such as dry mouth, constipation and drowsiness, may increase how often and how severe these side effects are experienced.

Oxybutynin may slow the digestive tract and thereby influence the adsorption of other oral medicines, or the use of this medicine together with other medicines may increase the effect of oxybutynin. Especially:

• Ketoconasole, itraconazole or fluconazole (used for the treatment of fungal infections).
• Erythromycin a macrolide antibiotic (used to treat bacterial infections).
• Biperiden, levodopa, or amantadine (used to treat Parkinson’s disease).
• Antihistamines (used in the treatment of allergies such as hayfever).
• Phenothiazines or clozapine (used to treat mental illness).
• Tricyclic antidepressants (used to treat depression).
• Dipyridamole (used to treat blood clotting problems).
• Atropine and other anticholinergic medicines (used for treatment in stomach disorders such as irritable bowel syndrome).

Using Kentera with food and drink

Oxybutynin may cause drowsiness or blurred vision. Drowsiness may be increased by consumption of alcohol.

Pregnancy and breast-feeding

Ask your doctor for advice before taking any medicine.

Kentera should not be used during pregnancy unless clearly necessary.

When oxybutynin is used during breast-feeding, a small amount is excreted in the mother’s milk. Use of oxybutynin while breast-feeding is therefore not recommended.

Driving and using machines

Because Kentera may produce drowsiness, somnolence, or blurred vision, patients should be advised to exercise caution when driving or using machinery.