Product Details

What you need to know before you take Plenvu
Do not take Plenvu:
• if you are allergic (hypersensitive) to the active substances or any of the other
ingredients of Plenvu (listed in section 6)
• if you have a blockage in your bowel (bowel obstruction)
• if you have an opening in the wall of your stomach or bowel (bowel perforation)
• if you have paralysis of the gut (ileus)
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• if you experience problems with food and fluid emptying from your stomach
(e.g. gastric paresis, gastric retention)
• if you suffer from phenylketonuria. This is a hereditary inability of the body to
use a particular amino acid. Plenvu contains a source of phenylalanine
• if your body is unable to produce enough glucose-6-phosphate dehydrogenase
• if you have a very dilated bowel (toxic megacolon)
Warnings and precautions
Talk to your doctor, pharmacist or nurse before taking Plenvu if any of the below are
applicable to you. If you:
• have heart problems and/or heart rhythm problems
• have kidney problems and/or dehydration
• have stomach or bowel problems, including bowel inflammation
• have problems with swallowing
• have a high or low blood salt level (e.g. sodium, potassium)
• have any other medical conditions (e.g. seizures)
Plenvu should not be given to patients with impaired consciousness without medical
supervision.
If you are in poor health or have a serious medical condition, you should be particularly
aware of the possible side effects listed in section 4. Contact your doctor, pharmacist or
nurse if you are concerned.
If you experience sudden abdominal pain or rectal bleeding when taking Plenvu for
bowel preparation, contact your doctor or seek medical advice immediately.
Children and adolescents
Plenvu is not recommended for use in children under 18 years of age.
Other medicines and Plenvu
Tell your doctor, pharmacist or nurse if you are taking, have recently taken or might
take any other medicines (including oral contraceptives).
Medicines taken by mouth may not be absorbed properly when taken within 1 hour
before the start of Plenvu.
If taking oral contraceptives you may need to use additional forms of contraception
(e.g. condom) to prevent pregnancy.
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Food and drink with Plenvu
On the day before the clinical procedure you can eat a light breakfast followed by a
light lunch.
For the Two-day split dosing schedule, OR the Day before dosing schedule you
must finish eating lunch at least 3 hours before you start taking Plenvu, after which
you may only consume clear fluids.
For the Morning only dosing schedule you may have clear soup and/or plain
yogurt for dinner (which should be completed by approximately 20.00H). You may
only consume clear fluids from after dinner on the evening before the clinical
procedure.
Note: For information regarding the dosing schedules refer to section 3.
No breakfast is allowed on the morning of the clinical procedure.
Continue to drink clear fluids before, during, and after you take Plenvu to help prevent
fluid loss (dehydration). It is important for you to drink the additional prescribed
amounts of clear fluids.
Examples of clear fluids are water, clear soups, herbal tea, black tea or coffee (without
milk), soft drinks/diluted cordials and clear fruit juices (without pulp).
Important:
• Do not drink alcohol, milk, anything coloured red or purple (e.g.
blackcurrant juice) or any other drinks containing pulp material.
• Do not eat while taking Plenvu and until after your clinical procedure.
Consumption of all fluids should be stopped at least:
• two hours before the clinical procedure when under general anaesthesia, or
• one hour before the clinical procedure without general anaesthesia.
If you need to thicken fluids in order to swallow them safely, Plenvu may counteract
the effect of the thickener.
Pregnancy, breast-feeding and fertility
There are no data on the use of Plenvu during pregnancy or breast-feeding and is
therefore not recommended. It should only be used if considered essential by the
doctor. If you are pregnant or breastfeeding, think you may be pregnant or are planning
to have a baby, ask your doctor, pharmacist or nurse for advice before taking Plenvu.
Driving and using machines
Plenvu does not affect your ability to drive or use machines.
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Plenvu contains sodium, potassium and a source of phenylalanine
This medicinal product contains 458.5 mmol (10.5 g) sodium per course of treatment.
This is to be taken into consideration by patients on a controlled sodium diet.
This medicinal product contains 29.4 mmol (1.1 g) potassium per course of treatment.
This should be taken into consideration by patients with reduced kidney function or
patients on a controlled potassium diet.
Plenvu contains a source of phenylalanine which may be harmful for people with
phenylketonuria. It also contains ascorbate which may be harmful for people with
glucose-6-phosphate dehydrogenase deficiency