Maloff Protect Tablets – Atovaquone and Proguanil, 36 Tablets
Nothing ruins a travel adventure quite like contracting a deadly disease. And when it comes to diseases, few are more dangerous than malaria. Maloff Protect is a preventative medicine used to combat the deadly disease malaria. It contains atovaquone and proguanil hydrochloride, which work together to halt the progression of the disease. For travelers headed to areas where malaria is endemic, Maloff Protect is an essential part of their preventive arsenal. Just one dose of Maloff Protect can offer up to three months of protection, so you can rest assured that you’re safe from this serious threat. Don’t let a little thing like malaria ruin your next big adventure – be sure to pack Maloff Protect!
For travelers headed to areas where malaria is endemic, Maloff Protect is an essential part of their preventive arsenal.
Maloff Protect is an antimalarial medication (malaria prophylaxis) that helps prevent malaria in individuals who are traveling to areas where the disease is present.
What is Malaria?
Malaria is a serious tropical disease that can be fatal if not treated promptly. A single mosquito bite leads to infection.
It’s important to be aware of the symptoms of malaria if you’re travelling to areas where there’s a high risk of the disease.
Symptoms of malaria can develop as quickly as 7 days after you’re bitten by an infected mosquito.
Typically, the time between being infected and when symptoms start (incubation period) is 7 to 18 days, depending on the specific parasite you’re infected with. However, in some cases it can take up to a year for symptoms to develop.
The initial symptoms of malaria are flu-like and include:
These symptoms are often mild and can sometimes be difficult to identify as malaria.
How to protect yourself from malaria?
People of any age can get malaria. It is a serious disease, but it is preventable. As well as taking Maloff Protect, it is very important that you also take steps to avoid being bitten by mosquitoes. The bite avoidance measures listed below should be used in combination for maximum effectiveness.
Use insect repellent on exposed areas of the skin.
Wear clothing that covers most of the body, especially after sunset as this is the time when mosquitoes are most active.
Sleep in a room with screened windows and doors or under a mosquito net (it is preferable to sleep under a mosquito net treated with insecticide if possible).
Close windows and doors at sunset, if they are not screened.
Sleep in a room with air-conditioning or a fan, as mosquitoes are less active in cooler temperatures.
Consider using an insecticide (mats, spray, plug-ins) to clear a room of insects or to stop mosquitoes from entering the room.
Can someone who is pregnant or breastfeeding use Maloff Protect?
If you are pregnant, think you may be pregnant or intend to get pregnant, or you are breastfeeding, do not take Maloff Protect unless your doctor tells you to.
Seek advice from your doctor or pharmacist if you are pregnant or breastfeeding and need to take an antimalarial.
Maloff Protect Reviews
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This medicine is available to buy over the counter. You do not need a prescription to buy Maloff Protect but you will be asked some questions about your medical health when you add it to your basket.
Always take this medicine exactly as described in this leaflet or as your doctor, nurse or pharmacist has told you. Check with your doctor or pharmacist if you are not sure.
Take Maloff Protect with food or a milky drink, where possible as this helps your body absorb the active ingredients.
It is best to take Maloff Protect at the same time each day.
Adults: Take one tablet once a day, as described below.
Start taking Maloff Protect one to two days before travelling to an area which has malaria.
Continue taking it every day during your stay.
Take Maloff Protect for another seven days after your return to a malaria-free area.
Take the full course of Maloff Protect for maximum protection. Stopping early puts you at risk of getting malaria, as it takes seven days to ensure that any parasites that may be in your blood after a bite from an infected mosquito are killed.
Maloff Protect is only available without a prescription for adults. It is not suitable for use in children or adolescents unless it has been prescribed for them by a doctor. If you are under 18 and you are visiting an area where there is malaria, talk to your doctor, nurse or pharmacist for advice.
If you take more Maloff Protect than you should
Contact a doctor or pharmacist for advice. If possible, show them the Maloff Protect pack.
If you forget to take Maloff Protect
It is important that you take the full course of Maloff Protect. If you forget to take a dose, take your next dose as soon as you remember. Then continue your treatment as before.
Do not take a double dose (two doses at the same time) to make up for a missed dose.
Only take an additional dose if you are sick (vomit) within one hour of taking Maloff Protect. See “Warnings and precautions” overleaf.
Don’t stop taking Maloff Protect unless your doctor or pharmacist tells you to. The only exception is if you experience one of the serious side effects listed in section 4 below.
Talk to your doctor or pharmacist if you need any advice.
If you have any further questions on the use of this product, ask your doctor or pharmacist.
Delivery Options
Delivery options
All deliveries are subject to the availability of the product and product sale conditions been met.
Order & Collect
Free next-day collection from In-Store
UK Delivery
Standard Delivery within the UK £3.50 Delivery time 3-4 days First Class Delivery within the UK £5.90 Delivery time 1-2 days Priority Delivery within the UK £7.10. Next day delivery by 1pm. Order must be placed by 1pm. Priority delivery is only available Monday to Thursday.
Europe Delivery
Standard Delivery within EEC from £12.50 Delivery time up to 5 days depending on the local delivery service within your country. Expedited Delivery within EEC £39.50 Delivery time 2 days. Delivery by DHL, UPS or TNT.
Rest of the World
Standard Delivery Rest of the World from £16.10 Delivery Time 10 – 15 Days Expedited Delivery Rest of the World £55.09 Delivery 5 days. Delivery service by DHL, TNT or UPS
are allergic to atovaquone and/or proguanil hydrochloride or any of the ingredients of this medicine (listed in section 6)
have kidney disease
have liver disease
Do not take Maloff Protect unless it has been prescribed for you by a doctor or other qualified prescriber if you:
are breastfeeding, pregnant or think you may be pregnant (see section ‘Pregnancy and Breastfeeding’)
are under 18 years old or weigh less than 40 kg
have ever had epilepsy, convulsions or fits
suffer from depression
have tuberculosis
Do not take Maloff Protect if you are already taking any of the following medicines:
etoposide, used to treat cancer
metoclopramide, used to treat nausea and vomiting
the antibiotics tetracycline, rifampicin or rifabutin
indinavir, efavirenz, zidovudine or certain medicines called protease inhibitors, used to treat human immunodeficiency virus (HIV)
warfarin, other coumarin based anticoagulants, or new oral anticoagulants (NOACs) such as dabigatran etexilate, rivaroxaban, and apixaban
Talk to your doctor or pharmacist for advice.
Warnings and precautions:
If you are sick (vomit) within one hour of taking your Maloff Protect tablet, take another dose straight away. If you don’t start vomiting until more than one hour after taking Maloff Protect, do not take another Maloff Protect tablet until your next dose is due, as it is likely that Maloff Protect will already be in your system
It is very important to take the full course of Maloff Protect. If you have to take extra tablets due to sickness, you may need to get some more
If you have been vomiting or have diarrhoea, it is especially important to use extra bite prevention, such as repellents and bed nets. The Maloff Protect you have taken may not be as effective because you may absorb less than you need
Tell your doctor or pharmacist if you have taken any medicines to prevent or treat malaria before and they have not worked or if you have had an allergic reaction to them. Maloff Protect may not be suitable for you.
Other medicines and Maloff Protect
Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines. This includes medicines that you buy without a prescription.
Do not take Maloff Protect if you are taking any of the medicines listed in the above section “Do not take Maloff Protect ”.
REMEMBER to tell your doctor or pharmacist if you start taking any other medicines while you’re taking Maloff Protect.
Maloff Protect with food and drink
Take Maloff Protect with food or a milky drink, where possible. This will increase the amount of Maloff Protect your body can absorb, and make your treatment more effective.
It is best if you swallow the tablets whole and do not crush them.
Pregnancy and breastfeeding
If you are pregnant, think you may be pregnant or intend to get pregnant, or you are breastfeeding, do not take Maloff Protect unless your doctor tells you to.
Pregnant women have an increased risk of developing severe malaria and a higher risk of fatality compared to non-pregnant women.
Seek advice from your doctor or pharmacist if you are pregnant or breastfeeding and need to take an antimalarial.
Driving and using machines
Maloff Protect makes some people feel dizzy. If you feel dizzy, do not drive, use machines or take part in activities where you may put yourself or others at risk.
Side Effects
Maloff Protect Side Effects
POSSIBLE SIDE EFFECTS
Like all medicines, Maloff Protect can cause side effects, although not everybody gets them.
IMPORTANT: If any side effect causes you to stop taking Maloff Protect, or if you vomit or have diarrhoea whilst taking Maloff Protect, you should continue to protect yourself against malaria as much as possible. Information on how to protect yourself from malaria is provided in section one of this leaflet. The bite avoidance measures listed in section one should be used in combination for maximum effectiveness.
Look out for the following severe reactions. They have occurred in a small number of people, but their exact frequency is unknown.
Stop taking Maloff Protect and contact a doctor immediately if you notice any of the following symptoms:
Severe allergic reactions – signs include:
rash and itching
sudden wheezing, tightness of the chest or throat, or difficulty breathing
swollen eyelids, face, lips, tongue or other part of the body
Severe skin reactions:
skin rash, which may blister and looks like small targets (central dark spots, surrounded by paler area with a dark ring around the edge) (erythema multiforme)
severe widespread rash with blisters and peeling skin, particularly occurring around the mouth, nose, eyes and genitals (Stevens-Johnson syndrome)
Most of the following side effects reported have been mild and have not lasted very long.
Very common: may affect more than 1 in 10 people
headache
feeling sick and being sick (nausea and vomiting)
stomach pain
diarrhoea
Common: may affect up to 1 in 10 people
dizziness
sleeping problems (insomnia)
strange dreams
depression
loss of appetite
fever
rash
cough
allergic reactions
itching (pruritus)
Common side effects, which may show up in your blood tests are:
reduced numbers of red blood cells (anaemia) which can cause tiredness, headaches and shortness of breath
reduced numbers of white blood cells (neutropenia) which may make you more likely to catch infections
low levels of sodium in the blood (hyponatraemia)
an increase in liver enzymes
Uncommon: may affect up to 1 to 100 people
anxiety
an unusual awareness of abnormal beating of the heart (palpitations)
swelling and redness of the mouth
red swollen patches on the skin (hives)
hair loss
Uncommon side effects that may show up in your blood tests:
an increase in amylase (an enzyme produced in the pancreas)
Rare: may affect up to 1 in 1,000 people
seeing or hearing things that are not there (hallucinations)
Other side effects:
Other side effects have occurred in a small number of people but their exact frequency is unknown.
pancytopenia (a decrease in all types of blood cells)
inflammation of the liver (hepatitis)
blockage of the bile ducts (cholestasis)
increase in heart rate (tachycardia)
inflammation of the blood vessels (vasculitis) which may be visible as red or purple raised spots on the skin but can affect other parts of the body
fits (seizures)
panic attacks, crying
nightmares
severe mental health problem in which the person loses contact with reality and is unable to think and judge clearly
mouth ulcers
blisters
peeling skin
increased sensitivity of the skin to sunlight
effects on your stomach (gastric intolerance)
Reporting of side effects
If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme Website: www.mhra.gov.uk/yellowcard. By reporting side effects, you can help provide more information on the safety of this medicine.
Ingredients
Maloff Protect Ingredients
What Maloff Protect contains
The active substances are atovaquone and proguanil hydrochloride. Each tablet contains 250 mg atovaquone and 100 mg proguanil hydrochloride.
The other ingredients are:
Core
Poloxamer 188, Microcrystalline Cellulose, Low-substituted Hydroxypropyl Cellulose, Povidone K30, Sodium Starch Glycolate Type A, Silica Colloidal anhydrous, Magnesium Stearate
Coating
Hypromellose, Titanium Dioxide (E171), Iron Oxide Red (E172), Macrogol 400, Macrogol 8000
How to Store
How to Store Maloff Protect
Keep this medicine out of the sight and reach of children.
Do not use this medicine after the expiry date which is stated on the carton and the blister after EXP. The expiry date refers to the last day of that month.
This medicine does not require any special storage conditions.
Do not throw away any medicines via wastewater or household waste. Ask your pharmacist how to throw away medicines you no longer use. These measures will help protect the environment.
72 HOURS OF UNPROTECTED SEX – Levonorgestrel Morning After Pill is an emergency contraceptive that can be used within 72 hours (3 days) of unprotected sex or if your usual contraceptive method has failed.
USE AFTER UNPROTECTED SEX – If you have had unprotected sex, take Levonorgestrel Morning After Pill as soon as possible. The sooner you take it, the more effective it will be.
IF YOUR USUAL CONTRACEPTIVE METHOD HAS FAILED – If you are using a barrier method of contraception eg condoms, spermicides, diaphragm etc but this has failed eg broken condom, spilt spermicide etc then you can use Levonorgestrel Morning After Pill
Taken to prevent and relieve the symptoms of acid reflux, including during pregnancy, and relieve the symptoms of conditions such as hiatus hernia, reflux oesophagitis (inflamed foodpipe) and symptoms of hoarseness and other voice disorders, sore throat and cough associated with reflux.
Aspirin 75mg Enteric Coated Tablets are principally used to prevent blood clots forming following a heart attack or stroke or to help prevent heart attacks and strokes in patients who have previously suffered from these conditions
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