Product Details

What you need to know before you take Mefenamic Acid Tablets

Do not take Mefenamic Acid Tablets: · if you are allergic (hypersensitive) to mefenamic acid or any of the other ingredients of this medicine (listed in section 6 “Contents of the pack and other information”); · if you are allergic to any other NSAIDs such as aspirin, ibuprofen or celecoxib; · if you have an inflammatory bowel disease such as Crohn’s disease or ulcerative colitis; · if you have a history of gastrointestinal conditions such as bleeding in the stomach, peptic ulcer, gastritis; · if you have severe heart, liver or kidney failure; · if you are in the last trimester of pregnancy (more than 6 months pregnant); · if you have had heart bypass surgery. Warnings and precautions Talk to your doctor or pharmacist before taking Mefenamic Acid Tablets if: · you are taking any other NSAIDs such as ibuprofen, diclofenac; · you are taking any other anti-inflammatory medicines, including steroids such as prednisolone; · you are taking medicines such as warfarin or clopidogrel, which are used to thin the blood; · you are taking selective serotonin medicines such as paroxetine, which are antidepressants; · you have liver or kidney problems, as your doctor may monitor their function before and during treatment; · you are trying to become pregnant (see section “Fertility”); · you are elderly (see section 3 “How to take Mefenamic Acid Tablets”); · previously taking painkillers such as aspirin have given you an upset stomach, or you have a history of stomach or digestive tract problems. Patients taking mefenamic acid can experience bleeding in the stomach or gut; · you are going to have a major operation or have a bleeding disorder, as mefenamic acid can affect how your blood clots (it can make you bleed more or for longer periods of time); · you have or have a history of asthma, as it may cause difficulties in breathing; · you have epilepsy; · you have a disorder of the connective tissue, such as Systemic Lupus Erythematosus (SLE); · you are dehydrated with symptoms of thirst, dry mouth, dry skin, dark urine, headache; · you have problems with your heart, have previously had a stroke, or you think you may be at risk of these conditions (e.g. if you have diabetes, high blood pressure, are a smoker, or have high cholesterol). Your doctor may carry out additional monitoring. Medicines such as Mefenamic Acid Tablets may be associated with a small increased risk of stroke or heart attack. Any such risk is more associated with high doses, and prolonged treatment. Do not exceed the recommended dose or treatment duration. Other medicines and Mefenamic Acid Tablets Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines. This includes any herbal medicines and medicines obtained without a prescription. Mefenamic Acid Tablets may affect other medicines and other medicines, in turn, may affect how well Mefenamic Acid Tablets work. Tell your doctor or pharmacist if you are taking: · medicines which can increase the chances of bleeding in the stomach or gut, or increase the risk of getting ulcers such as: – medicines used to treat arthritis and inflammation (corticosteroids); – medicines used to thin the blood (anti-platelet drugs such as warfarin, aspirin, clopidogrel); – anti-depressant medicines such as paroxetine, which are selective serotonin re- uptake inhibitors (SSRIs); – medicines which are anti-inflammatory, such as diclofenac, celecoxib; · aspirin, used in some heart conditions to stop your blood from clotting; · medicines used to treat high blood pressure, such as atenolol, ramipril, valsartan; · water tablets (diuretics), or medicines for the heart, such as digoxin, diltiazem, sotalol; · medicines used to treat diabetes, such as glibenclamide, glipizide; · medicines used to suppress the immune system, such as ciclosporin, methotrexate, tacrolimus; · medicines used to treat some types of depression, and mood swings, such as lithium; · a medicine called mifepristone which has been taken within the last 12 days. This is usually prescribed via hospitals; · quinolone or aminoglycoside antibiotics, used to treat infections; · zidovudine, used for HIV; · probenecid, used in special situations to protect the kidneys; · medicines which bind to protein in the blood (check with your pharmacist). Blood tests During treatment, your doctor may test your blood. Pregnancy, breast-feeding and fertility If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking any medicine. Pregnancy Mefenamic acid passes to your unborn baby. During the first six months of pregnancy, it is not known how mefenamic acid can affect your unborn baby. Your doctor or pharmacist will help you decide whether or not to take these tablets in the first six months of pregnancy. Mefenamic Acid Tablets should not be taken in the last three months of pregnancy, as this may prolong its duration and delay the onset of labour. This could also lead to bleeding in the mother or unborn baby. Breast-feeding Mefenamic acid passes into breast milk and can affect the baby. You should not breast-feed whilst taking these tablets, unless advised by your doctor. Fertility If you are trying to become pregnant, do not take these tablets as it may make getting pregnant more difficult. Speak to your doctor if you are trying to become pregnant or are having difficulties getting pregnant. Driving and using machines Mefenamic Acid Tablets may cause drowsiness, fatigue, dizziness or may affect your vision. If you experience any of these symptoms, you should not drive or operate machinery, or perform any tasks which may require you to be alert. Mefenamic Acid Tablets contain lactose and sodium · If you have been told by your doctor you have an intolerance to some sugars, contact your doctor before taking this medicinal product. · This medicine contains less than 1 mmol sodium (23 mg) per tablet, that is to say essentially ‘sodium-free’.