Product Details

What you need to know before you use
MENOPUR
Before starting treatment with MENOPUR, you and your partner
should be evaluated by a doctor for the causes of your fertility
problems. In particular you should be checked for the following
conditions so that any other appropriate treatment can be given:
• Underactive thyroid or adrenal glands
• High levels of a hormone called prolactin (hyperprolactinemia)
• Tumours of the pituitary gland (a gland located on the base of
the brain which produces certain hormones, including growth
hormones)
• Tumours of the hypothalamus (an area located under the part
of the brain called the thalamus which controls the conditions
within your body including body temperature and blood
pressure)
If you know you have any of the conditions listed above, please
tell your doctor before starting treatment with MENOPUR.
Do not use MENOPUR if:
• You are allergic (hypersensitive) to menotrophin or any of the
other ingredients of MENOPUR (listed in Section 6).
• You have a tumour in your pituitary gland.
• You have a tumour in the hypothalamus.
Also, if you are a woman do not use MENOPUR if:
• You have tumours of the womb (uterus), ovaries or
breasts.
• You have sacs of fluid known as cysts on your ovaries (ovarian
cysts) or enlarged ovaries that are not due to polycystic
ovarian disease (a condition that prevents eggs from being
released from the ovaries).
• You have bleeding from your vagina for an unknown
reason.
• You are having an early (premature) menopause.
• You have certain physical problems in your reproductive
organs (womb, fallopian tubes, ovaries or cervix).
• Your womb has been removed (hysterectomy).
• You have fibroid tumours (tumours in your womb that are not
cancer).
• You are pregnant or breast-feeding.
Also, if you are a man do not use MENOPUR if:
• You have cancer of your testicles.
• You have prostate cancer.
Do not use MENOPUR if any of the above applies to you. If you
are not sure, talk to your doctor, nurse or pharmacist before you
start using MENOPUR.

Warnings and precautions
Talk to your doctor or nurse if:
• You get pain or swelling of the stomach (abdomen)
• You get nausea or vomiting
• You get diarrhea
• You gain weight
• You have difficulty in breathing
• You get decreased urination (produce less urine)
Tell your doctor straight away, even if the symptoms develop
some days after the last injection has been given. These can be
signs of high levels of activity in the ovaries which might become
severe.
If these symptoms become severe, the infertility treatment
should be stopped and you should receive treatment in hospital.
Keeping to your recommended dose and careful monitoring
of your treatment will reduce your chances of getting these
symptoms.
If you stop using MENOPUR you might still experience these
symptoms. Please contact your doctor immediately if any of
these symptoms occur.
While you are being treated with this medicine, your doctor
will normally arrange for you to have ultrasound scans and
sometimes blood tests to monitor your response to treatment Being treated with hormones like MENOPUR can increase the
risk of:
• Ectopic pregnancy (pregnancy outside of the womb) if you
have a history of fallopian tube disease.
• Miscarriage
• Multiple pregnancy (twins, triplets, etc)
• Congenital malformations (physical defects present in baby at
birth).
Some women who have been given infertility treatment with
multiple medicines have developed tumours in the ovaries and
other reproductive organs. It is not yet known if treatment with
hormones like MENOPUR causes these problems.
Blood clot formation inside the blood vessels (veins or arteries)
are more likely to occur in women who are pregnant. Infertility
treatment can increase the chances of this happening, especially
if you are overweight or known with blood clotting disease
(thrombophilia) or if you or someone in your family (blood
relative) has had blood clots. Tell your doctor if you think this
applies to you.
Children
There is no relevent use of MENOPUR in children.
Other medicines and MENOPUR
Tell your doctor if you are taking, have recently taken or might
take any other medicines, including medicines obtained without
a prescription.
Clomiphene citrate is another medicine used in the treatment of
infertility. If MENOPUR is used at the same time as clomiphene
citrate the effect on the ovaries may be increased.
Pregnancy and breast-feeding
MENOPUR should not be used during pregnancy or breastfeeding.
Driving and using machines
MENOPUR is unlikely to affect your ability to drive and use
machines.
Important information about some of the ingredients of
MENOPUR
MENOPUR contains less than 1 mmol sodium (23 mg) per
dose, so it is essentially ‘sodium-free’. MENOPUR also contains
lactose (which is a type of sugar). If you have been told by your
doctor that you cannot tolerate or digest some sugars (have an
intolerance to some sugars), talk to your doctor before using this
medicine.

How to store MENOPUR
• Keep out of the sight and reach of children.
• Do not use MENOPUR after the expiry date which is stated
on the packaging. The expiry date refers to the last day of that
month.
• Before reconstitution, store in a refrigerator (2°C – 8°C).
• After reconstitution, the solution may be stored for a maximum
of 28 days at not more than 25°C.
• Do not freeze before or after reconstitution.
• Medicines should not be disposed of via wastewater or
household waste. Ask your pharmacist how to dispose of
medicines no longer required. These measures will help to
protect the environment.