Product Details

What you need to know before you take MigraKind

Do not take MigraKind: • If you’re allergic to sumatriptan, or any of the other ingredients of this medicine (listed in section 6) • If you have a heart problem such as narrowing of the arteries (Ischaemic heart disease) or chest pains (angina), or have already had a heart attack • If you have circulation problems in your legs that cause cramp-like pains when you walk (peripheral vascular disease) • If you have had a stroke or a mini-stroke (also called a transient ischaemic attack or TIA) • If you have high blood pressure. You may be able to use MigraKind if your high blood pressure is mild and is being treated • If you have serious liver disease • With other migraine medicines, including those which contain ergotamine, or similar medicine such as methysergide maleate; • or any triptan or 5HT1 agonist (such as naratriptan or zolmitriptan) • With any of the following anti-depressants: • MAOIs (monoamine oxidase inhibitors) or if you have taken an MAOI in the last 2 weeks For children under 18 years of age. If any of these apply to you: Tell your doctor, and don’t use MigraKind tablets. Take special care with MigraKind Talk to your doctor or pharmacist before using MigraKind. If you have any extra risk factors • If you are a heavy smoker, or using nicotine replacement therapy, and especially • If you are a man aged over 40, or • you are very overweight

you have diabetes • you have high cholesterol • you have a close relative who developed early heart disease – either your father or brother developed heart • disease before the age of 55, or your mother or sister developed heart disease before the age of 65. If three or more of the points above apply to you, you may be at higher risk of heart disease- see your doctor without taking If you are a woman who has been through the menopause. In very rare cases, people have developed serious heart conditions after using MigraKind, even though they had no signs of heart disease before. If any of the points above applies to you it could mean you have a greater risk of developing heart disease – so: • Tell your doctor so that your heart function can be checked before MigraKind. is prescribed for you. If you have a history of fits (seizures) Or if you have other conditions which might make it more likely that you’ll have a fit – for example, a head injury or alcoholism: • Tell your doctor so that you can be supervised more closely. If you have had high blood pressure MigraKind may not be suitable for you • Tell your doctor or pharmacist before using MigraKind, If you have liver or kidney disease If either of these apply to you: • Tell your doctor or pharmacist before using MigraKind, If you have an intolerance to some sugars • Tell your doctor so that you can be supervised more closely. If you are allergic to antibiotics called sulphonamides If so, you may also be allergic to MigraKind,If you know you are allergic to an antibiotic but you are not sure whether it is a sulphonamide: • Tell your doctor or pharmacist before using MigraKind. If you are taking anti-depressants called SSRIs (Selective Serotonin Reuptake Inhibitors) or SNRIs (Serotonin Noradrenaline Reuptake Inhibitors) • Tell your doctor or pharmacist before using MigraKind. Also see Other medicines and MigraKind, below. If you use MigraKind frequently. Using MigraKind too often may make your headaches worse. • Tell your doctor if this applies to you. He or she may recommend you stop using MigraKind.

If you feel pain or tightness in your chest after you use MigraKind These effects may be intense but they usually pass quickly. If they don’t pass quickly, or they become severe: Get medical help immediately. Section 4 (overleaf) has more information about these possible side effects. If three or more of the points above apply to you, you may be at higher risk of heart disease – see your doctor without taking MigraKind. If you are not sure, your pharmacist or doctor can help. • if your headaches usually last longer than 24 hours, or become more frequent • if you generally have four or more migraine attacks each month • if you do not recover completely in between your migraine attacks • if you are over 50 and this is your first headache of this type • if your migraine attacks get worse or become more frequent, or your symptoms change • if your migraine includes symptoms such as • weakness on one side of your body – clumsy and un-coordinated movements – reduced level of consciousness – a recent rash with a headache – double vision – tinnitus (ringing in the ears) – seizure (fit)- like movements The use of buprenorphine together with MigraKind can lead to serotonin syndrome, a potentially lifethreatening condition (see “Other medicines and MigraKind”). If any of the points in this list apply to you, and you haven’t already talked to a pharmacist or doctor about these, get their advice before taking MigraKind Other medicines and MigraKind Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines. This includes any herbal products or medicines you’ve bought without a prescription. Some medicines must not be taken with MigraKind and others may cause adverse effects if they are taken with MigraKind.

You must tell your doctor if you are taking: • ergotamine also used to treat migraine, or similar medicines such as methysergide (see section 2 Don’t use MigraKind).Don’t use MigraKind at the same time as these medicines. Stop taking these medicines at least 24 hours before using MigraKind. Don’t take any medicines which contain ergotamine or compounds similar to ergotamine again for at least 6 hours after using MigraKind. • other triptans/5-HT1 receptor agonists (such as naratriptan, rizatriptan, zolmitriptan), also used to treat migraine, (see section 2 Don’t use MigraKind). Don’t use MigraKind at the same time as these medicines. Stop taking these medicines at least 24 hours before using MigraKind. Don’t take another triptan/5-HT1 receptor agonist again for at least 24 hours after using MigraKind. • MAOIs used to treat depression. Don’t use MigraKind if you have taken these in the last 2 weeks. • SSRIs and SNRIs used to treat depression. Using MigraKind with these medicines can cause serotonin syndrome (a collection of symptoms which can include restlessness, confusion, sweating, hallucinations, increased reflexes, muscle spasms, shivering, increased heartbeat and shaking). Tell your doctor immediately if you are affected in this way. • St John’s Wort (Hypericum perforatum). Taking herbal remedies that contain St John’s Wort together with MigraKind may make side effects more likely. • Buprenorphine, naloxone: These medicines may interact with MigraKind and you may experience symptoms such as involuntary, rhythmic contractions of muscles, including the muscles that control movement of the eye, agitation, hallucinations, coma, excessive sweating, tremor, exaggeration of reflexes, increased muscle tension, body temperature above 380C.Contact your doctor when experiencing such symptoms. Pregnancy, breast-feeding and fertility • If you are pregnant, think you may be pregnant or are planning to have a baby, ask your doctor for advice before taking this medicine. There is only limited information about the safety of this medicine for pregnant women, though up till now there is no evidence of any increased risk of birth defects. Your doctor will discuss with you whether or not you should use this medicine while you are pregnant • Don’t breast-feed your baby for 12 hours after using this medicine. If you express any breast milk during this time, discard the milk and don’t give it to your baby. Driving and using machines Either the symptoms of migraine or your medicine may make you drowsy. If you are affected, do not drive or operate machinery. MigraKind contains Lactose If you have been told by your doctor that you have intolerance to some sugars, contact your doctor before taking this medicinal product