Product Details

What you need to know before you use Ondansetron 4mg Orodispersible Tablets

Do not use Ondansetron 4mg Orodispersible Tablets

• if you are allergic to ondansetron or any of the other ingredients of this medicine (listed in section 6)
• if you are allergic to other drugs belonging to the group of selective serotonin (5-HT3)-receptor antagonists (eg. granisetron, dolasetron)
• if you are taking apomorphine (used to treat Parkinson’s disease). For further information see section “Other medicines and Ondansetron 4mg Orodispersible Tablets”.

Warnings and precautions

Talk to your doctor, nurse or pharmacist before taking Ondansetron 4mg Orodispersible Tablets if:

• you have ever had heart problems
• you have an irregular or uneven heart beat (arrhythmia)
• you have liver problems
• you have a blockage in your gut or bowel or if you suffer from severe constipation
• you have problems with the levels of salts in your blood, such as potassium, sodium and magnesium
• you are going to have or have recently had your tonsils or adenoids removed, because treatment with Ondansetron 4mg Orodispersible Tablets may hide symptoms of internal bleeding
• this medicine is prescribed for a child below the age of 2 years or with a body surface of less than 0.6m² and / or weighing 10kg and below
• you have depression or other conditions that are treated with antidepressants.. The use of these medicines together with Ondansetron 4mg Orodispersible Tablets can lead to serotonin syndrome, a potentially life-threatening condition (see “Other medicines and Ondansetron 4mg Orodispersible Tablets”).

If you need to have a blood or urine test, you should tell the person performing the test that you are taking Ondansetron 4mg Orodispersible Tablets.

If you are not sure if any of the above apply to you, talk to your doctor, nurse or pharmacist before taking Ondansetron 4mg Orodispersible Tablets.

Other medicines and Ondansetron 4mg Orodispersible Tablets

Tell your doctor, nurse or pharmacist if you are taking, have recently taken or might take any other medicines. This includes medicines that you buy without a prescription and herbal medicines. This is because Ondansetron 4mg Orodispersible Tablets can affect the way some medicines work. Also some other medicines can affect the way Ondansetron 4mg Orodispersible Tablets works.

In particular, tell your doctor, nurse or pharmacist if you are taking any of the following medicines:

• Apomorphine (a medical substance for the treatment of Parkinson’s disease), as excessive drop in blood pressure and loss of consciousness have been reported when administering Ondansetron 4mg Orodispersible Tablets (Ondansetron) concomitantly with apomorphine.
• Phenytoin, carbamazepine (medicines used to treat epilepsy)
• Rifampicin (for treating serious bacterial infections, like TB)
• Antibiotics such as erythromycin
• Antifungal agents such as ketoconazole
• Tramadol (for managing pain)
• Anti-arrhythmics (used to treat irregular or fast heart beat)
• Beta-blockers (used to treat certain heart or eye problems, anxiety or prevent migraines)
• Medicines that can affect the heart (such as haloperidol or methadone)
• Cancer medicines (especially anthracyclines and trastuzumab)
• antidepressants such as SSRIs (selective serotonin reuptake inhibitors) used to treat depression and/or anxiety including fluoxetine, paroxetine, sertraline, fluvoxamine, citalopram, escitalopram; or
• SNRIs (serotonin noradrenaline reuptake inhibitors) used to treat depression and/or anxiety including venlafaxine, duloxetine
• Buprenorphine/opioids (medicinal products used for the treatment of pain or dependency on narcotics).

If you are not sure if any of the above applies to you, talk to your doctor, nurse or pharmacist before having Ondansetron 4mg Orodispersible Tablets.

Ondansetron 4mg Orodispersible Tablets with food and drink

You may take Ondansetron 4mg Orodispersible Tablets with food and drink.

Pregnancy and breast-feeding

Pregnancy:

Only use Ondansetron 4mg Orodispersible Tablets during the first trimester of pregnancy after discussion with your doctor of the potential benefits and risks to you and your unborn baby of the different treatment options. This is because Ondansetron 4mg Orodispersible Tablets can slightly increase the risk of a baby being born with cleft lip and/or cleft palate (openings or splits in the upper lip and/or the roof of the mouth).

If you are pregnant, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.

If you are a woman of childbearing potential you may be advised to use effective contraception.

Breast-feeding:

You should not breast-feed whilst using Ondansetron 4mg Orodispersible Tablets as it can pass into your breast milk.

Driving and using machines

Ondansetron 4mg Orodispersible Tablets has little or no effect on your ability to drive or use machines.