Product Details

What you need to know before you take Oruvail Capsules

Do not take Oruvail Capsules if: Ð You are allergic to: – ketoprofen – aspirin – any other Non-Steroidal Anti-Inflammatory Drug (NSAID) such as ibuprofen or indometacin – any of the other ingredients of Oruvail Capsules (listed in Section 6 below) Signs of an allergic reaction include: a rash, swallowing or breathing problems, swelling of your lips, face, throat or tongue. Ð You have or have ever had an ulcer or bleed in your stomach or intestine (gut). Ð You have severe heart problems. Ð You have severe liver or kidney problems. Ð You bruise more easily than usual and have bleeding that lasts a long time. Ð You are in the last 3 months of your pregnancy (see ‘Pregnancy and breast-feeding’ below). Do not take this medicine if any of the above apply to you. If you are not sure, talk to your doctor or pharmacist before using Oruvail Capsules. Warnings and precautions Talk to your doctor or pharmacist before taking your medicine if:  You are asthmatic.  You have ulcerative colitis or Crohn’s disease.  You have a disease affecting the skin, joints or kidneys called ‘Systemic Lupus Erythematosus’ (SLE).  You are 65 years of age or older.  You are planning to become pregnant or you have problems becoming pregnant. Oruvail Capsules may make it more difficult to become pregnant.  You have heart problems, previous stroke or think that you might be at risk of these conditions (if you have high blood pressure, diabetes or high cholesterol or are a smoker).  You are having or have had heart bypass surgery  You have an infection – please see heading ‘Infections’ below. Medicines such as Oruvail Capsules may be associated with a small increased risk of heart attack (myocardial infarction) or stroke. Any risk is more likely with high doses and prolonged treatment. Do not exceed the recommended dose or duration of treatment. -1- 11503340-11 Infections Oruvail Capsules may hide signs of infections such as fever and pain. It is therefore possible that Oruvail Capsules may delay appropriate treatment of infection, which may lead to an increased risk of complications. This has been observed in pneumonia caused by bacteria and bacterial skin infections related to chickenpox. If you take this medicine while you have an infection and your symptoms of the infection persist or worsen, consult a doctor without delay. If you are not sure if any of the above apply to you, talk to your doctor or pharmacist before taking Oruvail Capsules. Your doctor may need to keep a close check on you or give you a shorter course of treatment if:  You have high cholesterol or blood fats.  You are diabetic.  You smoke.  You have kidney or liver problems.  You are taking water tablets (diuretics).  You are taking medicines which increase potassium. Your doctor may carry out regular blood tests, particularly for checking the levels of potassium in your blood. If you are not sure if any of the above apply to you, talk to your doctor or pharmacist before taking Oruvail Capsules. Other medicine and Oruvail Capsules Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines. This includes medicines you buy without a prescription, including herbal medicines. This is because Oruvail Capsules can affect the way some other medicines work. Also some medicines can affect the way Oruvail Capsules work. In particular, tell your doctor if you are taking any of the following: • Other Non-Steroidal Anti-Inflammatory Drugs such as aspirin or ibuprofen • Water tablets (diuretics) • Medicines for high blood pressure or heart failure • Digoxin – used for controlling heart rate or helping in heart failure • Nicorandil – used for treating chest pain • Medicines to stop your blood clotting such as heparin, warfarin, clopidogrel, ticlopidine, dabigatran, apixaban, rivaroxaban or edoxaban • Medicines to dissolve blood clots such as streptokinase, alteplase, reteplase or tenecteplase • Medicines for infections (antibiotics) such as ciprofloxacin, levofloxacin or ofloxacin • Medicines for depression such as fluoxetine, sertraline, citalopram or paroxetine • Corticosteroids – used for inflammation such as hydrocortisone, betamethasone or prednisolone • Ciclosporin – used after an organ transplantation to help prevent rejection • Mifepristone – used to terminate a pregnancy. It is important that Oruvail Capsules are not taken for 8-12 days after taking Mifepristone. • Lithium – used for some types of mental illness • Methotrexate – used for some types of cancer or psoriasis • Pentoxifylline – used to help poor blood circulation in limbs • Tenofovir – used for HIV • Tacrolimus – used after an organ transplant • Probenecid – used for gout • Zidovudine – used for HIV Pregnancy and breast-feeding Do not take Oruvail Capsules if you are in the last 3 months of pregnancy as it could harm your unborn baby. It may affect your and your baby’s tendency to bleed and cause labour to be later or longer than expected. You should not take Oruvail Capsules during the first 6 months of pregnancy unless absolutely necessary and advised by your doctor. If you need treatment during this period or while you are trying to get pregnant, the lowest dose for the shortest time possible should be used. If taken for more than a few days from 20 weeks of pregnancy onward, Oruvail Capsules can cause kidney problems in your unborn baby that may lead to low levels of amniotic fluid that surrounds the baby (oligohydramnios) or narrowing of a blood vessel (ductus arteriosus) in the heart of the baby. If you need treatment for longer than a few days, your doctor may recommend additional monitoring. You should not breast-feed if you are using Oruvail Capsules. This is because small amounts may pass into mothers’ milk. Ask your doctor or pharmacist for advice before taking any medicine if you are pregnant or breast-feeding. Driving and using machines You may feel sleepy, dizzy, faint, your eyesight may be affected or you may have a fit while taking this medicine. If this happens, do not drive or use any tools or machines. Oruvail Capsules contain sugar. Take this into account if you have diabetes