Product Details

Product Information of Pantoprazole Injection 40mg

What you need to know before you use Pantoprazole

Do not use Pantoprazole – If you are allergic (hypersensitive) to pantoprazole or any of the other ingredients of this medicine (see section 6). – If you are allergic to medicines containing other proton pump inhibitors. Warnings and precautions – If you have severe liver problems. Please tell your doctor if you ever had problems with your liver in the past. He will check your liver enzymes more frequently. In the case of a rise of liver enzymes, the treatment should be stopped. – If you have reduced body stores or risk factors for reduced vitamin B12 and receive long-term treatment with pantoprazole. As with all acid reducing agents, pantoprazole may lead to a reduced absorption of vitamin B12. – If you are taking a medicine containing atazanavir (for the treatment of HIV-infection) at the same time as pantoprazole, ask your doctor for specific advice. – People who take multiple daily doses of proton pump inhibitor medicines for a long period of time (a year or longer) may have an increased risk of fractures of the hip, wrist or spine. Talk to your doctor about your risk of bone fracture if you take Pantoprazole. – If you have low magnesium levels in your body. This problem can be serious. Low magnesium can happen in some people who take proton pump inhibitor medicine for at least 3 months. If low magnesium levels happen, it is usually after a year of treatment. You may or may not have symptoms of low magnesium. Talk to your doctor before taking Pantoprazole: – if you have ever had a skin reaction after treatment with a medicine similar to Pantoprazole that reduces stomach acid; – if you are due to have a specific blood test (Chromogranin A). If you get a rash on your skin, especially in areas exposed to the sun tell your doctor as soon as you can, as you may need to stop your treatment with Pantoprazole. Remember to also mention any other ill-effects like pain in your joints. Tell your doctor immediately if you notice any of the following symptoms: – an unintentional loss of weight – vomiting, particularly if repeated – difficulty in swallowing or pain when swallowing – vomiting blood; this may appear as dark coffee grounds in your vomit – you look pale and feel weak (anaemia) – you notice blood in your stools, which may be black or tarry in appearance – chest pain – stomach pain – severe and/or persistent diarrhoea, as Pantoprazole has been associated with a small increase in infectious diarrhoea. Your doctor may decide that you need some tests to rule out malignant disease because pantoprazole also alleviates the symptoms of cancer and could cause delay in diagnosing it. If your symptoms continue in spite of your treatment, further investigations will be considered. Children and adolescents Pantoprazole is not recommended for use in children as it has not been proven to work in children below 18 years of age. Other medicines and Pantoprazole Tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription. – Medicines such as ketoconazole, itraconazole and posaconazole (used to treat fungal infections) or erlotinib (used for certain types of cancer) because Pantoprazole may stop these and other medicines from working properly. – Warfarin and phenprocoumon, which affect the thickening, or thinning of the blood. You may need further checks. – Atazanavir (used to treat HIV-infection). – Methotrexate (used to treat rheumatoid arthritis, psoriasis and cancer) – if you are taking methotrexate your doctor may temporarily stop your Pantoprazole treatment because pantoprazole can increase levels of methotrexate in the blood. In the case of combination therapy, the patient leaflets of the respective medicines should be observed. Pregnancy, breast-feeding and fertility If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine. There are no adequate data from the use of pantoprazole in pregnant women. Excretion into human milk has been reported. You should use this medicine only if your doctor considers the benefit for you greater than the potencial risk for your unborn child or baby. Driving and using machines If you experience side effects like dizziness or disturbed vision, you should not drive or operate machines. Pantoprazole contains less than 1 mmol sodium (23 mg) per vial, i.e. is essentially ‘sodium- free’.