Side Effects

Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them. Stop taking Piroxicam capsules and contact your doctor immediately if you notice signs of: • an allergic reaction: asthma or worsening of asthma, narrowing of the airways causing difficulty breathing/wheezing, rash, irregular raised patches with severe itching (hives), swelling of the face, lips, throat or tongue, blood vessel inflammation, serum sickness (rash, fever, joint pain, enlarged lymph nodes) • allergic reaction involving purple spots on the skin, joint pain, abdominal pain and kidney dysfunction (Henoch-Schoenlein purpura) • skin reactions such assevere rash involving reddening, peeling and swelling of the skin that resembles severe burns (toxic epidermal necrolysis), severe form of skin rash with flushing, fever, blisters or ulcers (StevensJohnson syndrome). See section 2 • stomach or intestinal bleeding, ulceration or perforation: pass blood in your faeces (stools/motions), pass black tarry stools, vomit blood or dark particles that look like coffee grounds • liver disease (fatigue, weakness, loss of appetite, weight loss, abdominal pain, fever) or abnormal liver function (abnormal test results continue or worsen), liver disease causing yellowing of the skin or whites of the eyes (jaundice), inflammation of the liver (hepatitis). • kidney disease or failure • heart: water retention, high blood pressure, heart failure. Medicines such as Piroxicam may be associated with a small increased risk of heart attack (“myocardial infarction”) or stroke • indigestion or heartburn. Abdominal pain (pains in your stomach) or other abnormal stomach symptoms • inflamed pancreas (which may lead to severe pain in the upper abdomen or back) • hallucinations (seeing or hearing things that are not there). Tell your doctor if you notice any of the following side effects or notice any other effects not listed: Common (may affect up to 1 in 10 people): • changes in the red blood cells which may result in unusual bruising or bleeding • changes in the white blood cells which may result in increased risk of infection • anorexia • increase in blood sugar levels • dizziness • headache • vertigo (a spinning sensation) • drowsiness • ringing in ears (tinnitus) • abdominal pain/discomfort • constipation • diarrhoea • wind • feeling sick (nausea) • being sick (vomiting) • indigestion • itching • skin rash • swelling of the feet, hands or other parts of the body (oedema) • weight increase. Uncommon (may affect up to 1 in 100 people): • blurred vision • fast or pounding heartbeat • sore mouth and/or lips • decreased/low blood sugar level. Rare (may affect up to 1 in 1,000 people): • kidney inflammation • kidney damage • change in urine output or appearance • kidney pain or pain in abdomen. Not known (frequency cannot be estimated from the available data): • abnormalities in the blood e.g. decreased haemoglobin • fluid retention • depression • dream abnormalities • changes in sleep patterns • mental confusion • mood alterations • nervousness • pins and needles • eye irritations • swollen eyes • hearing impairment • high blood pressure • inflammation of the blood vessels • shortness of breath • constriction of the muscles lining the airways of lungs (bronchial) • nose bleeds • inflammation of the stomach lining (gastritis) • stomach (peptic) ulcers • upset stomach • kidney inflammation possibly causing blood in the urine or pinkish urine, rashes, joint pain, breathing problems or tiredness • hair loss • rashes, peeling, redness, tenderness, thickening or scaling of skin • fixed drug eruption (may look like round or oval patches of redness and swelling of the skin), blistering (hives), itching • loosening or splitting of fingernails • increased sensitivity of the skin to sunlight • decreased fertility • feeling unwell, general aches and pains • weight decrease.

Reporting of side effects

If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme at: www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store. By reporting side effects you can help provide more information on the safety of this medicine