Product Details

What you need to know before you take Trimethoprim Tablets

Do NOT take Trimethoprim Tablets if you: • are allergic (hypersensitive) to trimethoprim or to any of the other ingredients (see section 6, Contents of the pack and other information) • suffer from severe liver problems • are pregnant • suffer from any blood disorders such as anaemia Trimethoprim should not be administered to premature babies or infants under 4 months of age. The tablet form is NOT recommended for use in children under 6 years – the oral liquid form should be used. Warnings and precautions Talk to your doctor or pharmacist before taking Trimethoprim Tablets if you: • are pregnant • suffer from kidney problems/kidney disease or are having dialysis treatment • have a deficiency (are low) in folic acid (may cause anaemia) are at greater risk of high levels of potassium in your blood (hyperkalaemia), e.g. the elderly or those on higher doses • suffer from porphyria (a disorder that causes skin sensitivity to light, pain attacks and muscle weakness) • have fructose intolerance or an intolerance to some sugars. You should let your doctor know and ask his/her advice if you suffer from or have ever had any of the above. Trimethoprim can increase potassium blood levels. Patients at risk of increased potassium blood levels include those with kidney problems, poorly controlled diabetes, or those on certain medicines or potassium supplements. The symptoms of severe hyperkalaemia might include muscle cramps, irregular heart rhythm, diarrhoea, nausea, dizziness or headache. Your doctor may perform blood tests to monitor your potassium blood levels. Your doctor may wish to do regular blood tests if you need long-term treatment or are prone to anaemia. Children This dosage form is not suitable for use in children younger than 6 years. Other medicines and Trimethoprim Tablets Please inform your doctor or pharmacist if you are taking, or have recently taken any other medicines, even those not prescribed. Your medicine may interfere with other medicines that you are taking. Take care with the following medicines: • rifampicin (antibiotic), used to treat TB • anticoagulants (to prevent clots from forming in the blood e.g. warfarin) • immunosuppressant drugs – used in cancer treatment (e.g. methotrexate) or to treat organ rejection after transplant (e.g. azathioprine or ciclosporin) • digoxin, to treat certain heart conditions • phenytoin, to treat epilepsy • pyrimethamine and dapsone, used to treat malaria • bone marrow depressants. • potassium supplements • medicines known as ACE inhibitors and angiotensin II antagonists (used to treat high blood pressure and certain heart conditions). • heparin (used to treat and prevent blood clots) • repaglinide, used to treat diabetes • diuretics (water tablets such as eplerenone, spironolactone, amiloride or triamterene) • procainamide, to treat abnormal heart rhythm. Pregnancy and breast-feeding If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine. Trimethoprim should not be used in pregnancy. DO NOT take Trimethoprim Tablets if you are pregnant. If you are breast-feeding, ask your doctor or pharmacist for advice before taking this medicine. Driving and using machines There is no evidence to suggest that Trimethoprim Tablets affect the ability to drive or operate machinery. Trimethoprim Tablets contain lactose If your doctor has told you that you have an intolerance to some sugars, contact your doctor before taking this medicinal product.