Introducing Zoladex Injection 10.8mg – Goserelin Injection 10.8mg, also known as Zoladex LA, a revolutionary product that can help in the treatment of prostate cancer. This implant is designed to reduce the production of testosterone, which is a hormone that can contribute to the growth of prostate cancer cells.
Zoladex Injection 10.8mg (Zoladex LA) is a long-acting form of the medication and is administered every 12 weeks. It contains a powerful medicine called goserelin, which is part of a group of drugs known as LHRH analogues. These drugs are used to treat a variety of conditions, including prostate cancer, endometriosis, and breast cancer.
The implant is easy to use and is inserted under the skin by a healthcare professional. Once inserted, it works continuously to suppress testosterone production in the body. This can help to slow the growth and spread of cancer cells, and improve overall quality of life for those living with prostate cancer.
If you or a loved one is struggling with prostate cancer, Zoladex Injection – Goserelin Implant may be able to help. Talk to your healthcare provider today to learn more about this innovative treatment option.
What is Prostate Cancer?
Prostate cancer is the most frequently diagnosed cancer among men in the UK. The disease typically progresses slowly, and therefore may remain asymptomatic for a considerable period. Symptoms associated with prostate cancer typically manifest once the prostate has enlarged enough to impact the urethra, the tube that transports urine from the bladder to the penis. Indications of prostate cancer may include an increased frequency of urination, straining while urinating, and a sense that the bladder has not fully emptied. While these symptoms should not be disregarded, they are not necessarily indicative of prostate cancer, as they can also be caused by other conditions, such as prostate enlargement.
When this happens, you may notice things like:
an increased need to pee
straining while you pee
a feeling that your bladder has not fully emptied
These symptoms should not be ignored, but they do not mean you have prostate cancer.
It’s more likely they’re caused by something else, such as prostate enlargement.
WHAT IS THE PROSTATE?
The prostate is a small gland in the pelvis, found only in men.
About the size of a satsuma, it’s located between the penis and the bladder, and surrounds the urethra.
The main function of the prostate is to produce a thick white fluid that creates semen when mixed with the sperm produced by the testicles.
The causes of prostate cancer are largely unknown. But certain things can increase your risk of developing the condition.
The chances of developing prostate cancer increase as you get older. Most cases develop in men aged 50 or older.
For reasons not yet understood, prostate cancer is more common in men of African-Caribbean or African descent, and less common in Asian men.
Men whose father or brother were affected by prostate cancer are at slightly increased risk themselves.
Recent research also suggests that obesity increases the risk of prostate cancer.
TESTS FOR PROSTATE CANCER
There’s no single test for prostate cancer.
All the tests used to help diagnose the condition have benefits and risks that your doctor should discuss with you.
The most commonly used tests for prostate cancer are:
For many men with prostate cancer, treatment is not immediately necessary.
If the cancer is at an early stage and not causing symptoms, your doctor may suggest either “watchful waiting” or “active surveillance”.
The best option depends on your age and overall health. Both options involve carefully monitoring your condition.
Some cases of prostate cancer can be cured if treated in the early stages.
Treatments include:
surgically removing the prostate
radiotherapy – either on its own or alongside hormone therapy
Some cases are only diagnosed at a later stage, when the cancer has spread.
If the cancer spreads to other parts of the body and cannot be cured, treatment is focused on prolonging life and relieving symptoms.
All treatment options carry the risk of significant side effects, including erectile dysfunction and urinary symptoms, such as needing to use the toilet more urgently or more often.
For this reason, some men choose to delay treatment until there’s a risk the cancer might spread.
Newer treatments, such as high-intensity focused ultrasound (HIFU) and cryotherapy, aim to reduce these side effects.
Some hospitals may offer them as an alternative to surgery, radiotherapy or hormone therapy.
But the long-term effectiveness of these treatments is not known yet.
LIVING WITH PROSTATE CANCER
Prostate cancer is typically characterized by a slow progression, allowing individuals to live for several decades without the manifestation of symptoms or the need for treatment. Despite this, the diagnosis of prostate cancer can have a significant impact on one’s life, with potential side effects from treatment and an understandable risk of experiencing anxiety or depression. Discussing the condition with trusted family members, friends, family doctors, and support groups for men with prostate cancer can prove to be beneficial. Additionally, financial assistance is available to individuals experiencing a reduced ability to work due to prostate cancer.
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Can you buy Zoladex Injection 10.8mg Over the counter?
Zoladex Injection 10.8mg is not available to buy over the counter. You need a prescription to buy Zoladex Injection 10.8mg
Brand
Zoladex
How To Use
How to use Zoladex LA
The Zoladex LA 10.8 mg Implant will be injected under the skin on your stomach every 12 weeks. This will be done by your doctor or nurse.
It is important that you keep having Zoladex LA treatment, even if you are feeling well.
Keep having this treatment until your doctor decides that it is time for you to stop.
Your next appointment
You should be given a Zoladex LA injection every 12 weeks.
Always remind the doctor or nurse to set up an appointment for your next injection.
If you are given an appointment for your next injection which is earlier or later than 12 weeks from your last injection, tell your doctor or nurse.
If it has been more than 12 weeks since your last injection, contact your doctor or nurse so that you can receive your injection as soon as possible.
Delivery Options
Delivery options
All deliveries are subject to the availability of the product and product sale conditions been met.
Order & Collect
Free next-day collection from In-Store
UK Delivery
Standard Delivery within the UK £3.50 Delivery time 3-4 days First Class Delivery within the UK £5.90 Delivery time 1-2 days Priority Delivery within the UK £7.10. Next day delivery by 1pm. Order must be placed by 1pm. Priority delivery is only available Monday to Thursday.
Europe Delivery
Standard Delivery within EEC from £12.50 Delivery time up to 5 days depending on the local delivery service within your country. Expedited Delivery within EEC £39.50 Delivery time 2 days. Delivery by DHL, UPS or TNT.
Rest of the World
Standard Delivery Rest of the World from £16.10 Delivery Time 10 – 15 Days Expedited Delivery Rest of the World £55.09 Delivery 5 days. Delivery service by DHL, TNT or UPS
if you are allergic to goserelin or any of the other ingredients of this medicine (listed in section 6).
if you are a woman.
Do not have Zoladex LA if any of the above apply to you. If you are not sure, talk to your doctor, pharmacist or nurse before having Zoladex LA.
Warnings and precautions
Talk to your doctor, pharmacist or nurse before using Zoladex LA:
if you have problems passing urine (water) or problems with your back.
if you have diabetes.
if you have high blood pressure.
if you have any condition that affects the strength of your bones, especially if you are a heavy drinker, a smoker, have a family history of osteoporosis (a condition that affects the strength of your bones) or take anticonvulsants (medicines for epilepsy or fits) or corticosteroids (steroids).
if you have any heart or blood vessel conditions, including heart rhythm problems (arrhythmia), or are being treated with medicines for these conditions. The risk of heart rhythm problems may be increased when using Zoladex LA.
There have been reports of depression in patients taking Zoladex which may be severe. If you are taking Zoladex and develop depressed mood, inform your doctor.
Medicines of this type can cause a reduction in bone calcium (thinning of bones).
If you go into hospital, tell the medical staff that you are having Zoladex LA.
Children
Zoladex LA should not be given to children.
Other medicines and Zoladex LA
Tell your doctor, pharmacist or nurse if you are taking, have recently taken or might take any other medicines. This includes medicines that you buy without a prescription and herbal medicines.
Zoladex LA might interfere with some medicines used to treat heart rhythm problems (e.g. quinidine, procainamide, amiodarone and sotalol) or might increase the risk of heart rhythm problems when used with some other drugs (e.g. methadone (used for pain relief and part of drug addiction detoxification), moxifloxacin (an antibiotic), antipsychotics used for serious mental illnesses).
Driving and using machines
Zoladex LA is not likely to affect you being able to drive or use any tools or machines.
How to store Zoladex LA
Your doctor may give you a prescription so that you can get your medicine from the pharmacy and give it to your doctor when you see him or her again.
Keep this medicine out of the sight and reach of children.
Keep it in its original package and do not break the seal.
Do not store it above 25°C.
Do not use this medicine after the expiry date which is stated on the carton. The expiry date refers to the last day of that month.
Do not throw away any medicines via wastewater or household waste. Ask your pharmacist how to throw away medicines you no longer use. These measures will help protect the environment.
Side Effects
Like all medicines, this medicine can cause side effects, although not everybody gets them.
Allergic reactions:
These are rare. The symptoms can include sudden onset of:
Rash, itching or hives on the skin.
Swelling of the face, lips or tongue or other parts of the body.
Shortness of breath, wheezing or trouble breathing.
If this happens to you, see a doctor straight away.
Injection site injury (including damage to blood vessels in the abdomen) has been reported following injection of Zoladex LA. In very rare cases this has caused severe bleeding. Contact your doctor immediately if you experience any of the following symptoms:
Abdominal pain.
Abdominal distension.
Shortness of breath.
Dizziness.
Low blood pressure and/or any altered levels of consciousness.
Other possible side effects:
Very common (may affect more than 1 in 10 people)
Hot flushes and sweating. Occasionally these side effects may continue for some time (possibly months) after stopping Zoladex.
A reduced sex drive and impotence.
Common (may affect up to 1 in 10 people)
Pain in your lower back or problems passing urine. If this happens, talk to your doctor.
Bone pain at the beginning of treatment. If this happens, talk to your doctor.
Thinning of your bones.
Rises in blood sugar levels.
Tingling in your fingers or toes.
Skin rashes.
Weight gain.
Pain, bruising, bleeding, redness or swelling where Zoladex LA is injected.
Reduced heart function or heart attack.
Changes in blood pressure.
Swelling and tenderness of your breasts.
Changes in your mood (including depression).
Uncommon (may affect up to 1 in 100 people)
Pain in the joints.
Very rare (may affect up to 1 in 10,000 people)
Psychiatric problems called psychotic disorders which may include hallucinations (seeing, feeling or hearing things that are not there), disordered thoughts and personality changes. This is very rare.
The development of a tumour of the pituitary gland in your head or, if you already have a tumour in your pituitary gland, Zoladex LA may make the tumour bleed or collapse. These effects are very rare. Pituitary tumours can cause severe headaches, feeling or being sick, loss of eyesight and becoming unconscious.
Not known (frequency cannot be estimated from the available data)
Hair loss.
Changes in your blood.
Liver problems.
A blood clot in your lungs causing chest pain or shortness of breath.
Inflammation of the lungs. The symptoms may be like pneumonia (such as feeling short of breath and coughing).
Changes in ECG (QT prolongation).
Do not be concerned by this list of possible side effects. You may not get any of them.
Reporting of side effects
If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme, Website: www.mhra.gov.uk/yellowcard. By reporting side effects you can help provide more information on the safety of this medicine.
Ingredient
What Zoladex LA 10.8 mg Implant contains
The active substance is goserelin. Each Zoladex LA 10.8 mg Implant contains 10.8 mg of goserelin.
The other ingredient is lactide/glycolide copolymer which is an inactive substance.
What Zoladex LA 10.8 mg Implant looks like and contents of the pack
Zoladex LA 10.8 mg Implant comes as an implant (a very small pellet) in a pre-filled syringe, ready to be used by the doctor or nurse.
Zoladex LA 10.8 mg Implant is produced in packs of one implant (injection).
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